Matches in SemOpenAlex for { <https://semopenalex.org/work/W2903854404> ?p ?o ?g. }
- W2903854404 endingPage "82" @default.
- W2903854404 startingPage "79" @default.
- W2903854404 abstract "Background Toxoplasmosis is a cosmopolitan parasitic disease caused by Toxoplasma gondii (T. gondii). Blood transfusion is a probable route of T. gondii transmission. Due to lack of information about seroprevalence of T. gondii in healthy blood donors, this study was aimed to determine the chronic and acute infection using serological and molecular methods. Material and methods In this cross-sectional investigation, 380 samples were collected from donated bloods. Anti-Toxoplasma IgG and IgM antibodies were examined using enzyme-linked immunosorbent assay (ELISA). Also, all IgG positive samples were tested by IgG avidity test. Eventually, to detection of active infection, DNA was extracted from IgM positive and low IgG avidity samples and then tested using nested-polymerase chain reaction (PCR). Results Among 380 blood donors, 131 (34.47%) were positive for only anti-T. gondii IgG, 2 (0.5%) were positive for only anti-T. gondii IgM, and 11 (2.9%) were positive for both IgG and IgM antibodies. Then, 142 samples (131 IgG + and 11 IgG +IgM +) were evaluated using IgG avidity test. Of these, 115 (81%) had high avidity IgG indicates past infection; 16 (11.26%) had low avidity IgG representing recent infection, and 11 (7.74%) were equivocal. With nested PCR, 20 samples of 50 seropositive samples were diagnosed positive. Conclusion Detected active infection using nested-PCR draws attention to the possibility of T. gondii infection via blood transfusion which emphasizes the importance of parasite DNA screening before donation of blood in high risk groups such as: multi-transfused persons, immunosuppressed patient, and pregnant women." @default.
- W2903854404 created "2018-12-22" @default.
- W2903854404 creator A5007999981 @default.
- W2903854404 creator A5042421537 @default.
- W2903854404 creator A5042957176 @default.
- W2903854404 creator A5054955085 @default.
- W2903854404 creator A5060335533 @default.
- W2903854404 date "2019-02-01" @default.
- W2903854404 modified "2023-10-03" @default.
- W2903854404 title "Seroprevalence and molecular detection of Toxoplasma gondii in healthy blood donors in southwest Iran" @default.
- W2903854404 cites W1567282576 @default.
- W2903854404 cites W1641280389 @default.
- W2903854404 cites W1975781845 @default.
- W2903854404 cites W1989683412 @default.
- W2903854404 cites W2005707399 @default.
- W2903854404 cites W2024326117 @default.
- W2903854404 cites W2027723667 @default.
- W2903854404 cites W2033313061 @default.
- W2903854404 cites W2039034637 @default.
- W2903854404 cites W2042768637 @default.
- W2903854404 cites W2048625606 @default.
- W2903854404 cites W2055009787 @default.
- W2903854404 cites W2059842053 @default.
- W2903854404 cites W2096873907 @default.
- W2903854404 cites W2294411093 @default.
- W2903854404 cites W2294487746 @default.
- W2903854404 cites W2314629239 @default.
- W2903854404 cites W2534040426 @default.
- W2903854404 cites W2590027458 @default.
- W2903854404 cites W2607285488 @default.
- W2903854404 cites W2620244386 @default.
- W2903854404 cites W2622826692 @default.
- W2903854404 cites W2702794700 @default.
- W2903854404 cites W2734457671 @default.
- W2903854404 cites W2738123315 @default.
- W2903854404 cites W2784190971 @default.
- W2903854404 cites W2785781569 @default.
- W2903854404 cites W2797558436 @default.
- W2903854404 cites W2800022116 @default.
- W2903854404 cites W2802176098 @default.
- W2903854404 cites W2885647643 @default.
- W2903854404 cites W4229743528 @default.
- W2903854404 doi "https://doi.org/10.1016/j.transci.2018.12.003" @default.
- W2903854404 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30579749" @default.
- W2903854404 hasPublicationYear "2019" @default.
- W2903854404 type Work @default.
- W2903854404 sameAs 2903854404 @default.
- W2903854404 citedByCount "18" @default.
- W2903854404 countsByYear W29038544042019 @default.
- W2903854404 countsByYear W29038544042020 @default.
- W2903854404 countsByYear W29038544042021 @default.
- W2903854404 countsByYear W29038544042022 @default.
- W2903854404 countsByYear W29038544042023 @default.
- W2903854404 crossrefType "journal-article" @default.
- W2903854404 hasAuthorship W2903854404A5007999981 @default.
- W2903854404 hasAuthorship W2903854404A5042421537 @default.
- W2903854404 hasAuthorship W2903854404A5042957176 @default.
- W2903854404 hasAuthorship W2903854404A5054955085 @default.
- W2903854404 hasAuthorship W2903854404A5060335533 @default.
- W2903854404 hasConcept C104317684 @default.
- W2903854404 hasConcept C157431215 @default.
- W2903854404 hasConcept C159047783 @default.
- W2903854404 hasConcept C159654299 @default.
- W2903854404 hasConcept C179223381 @default.
- W2903854404 hasConcept C203014093 @default.
- W2903854404 hasConcept C2778062946 @default.
- W2903854404 hasConcept C2778128430 @default.
- W2903854404 hasConcept C2778494684 @default.
- W2903854404 hasConcept C2780014101 @default.
- W2903854404 hasConcept C2780898057 @default.
- W2903854404 hasConcept C45189115 @default.
- W2903854404 hasConcept C49105822 @default.
- W2903854404 hasConcept C55493867 @default.
- W2903854404 hasConcept C71924100 @default.
- W2903854404 hasConcept C86803240 @default.
- W2903854404 hasConceptScore W2903854404C104317684 @default.
- W2903854404 hasConceptScore W2903854404C157431215 @default.
- W2903854404 hasConceptScore W2903854404C159047783 @default.
- W2903854404 hasConceptScore W2903854404C159654299 @default.
- W2903854404 hasConceptScore W2903854404C179223381 @default.
- W2903854404 hasConceptScore W2903854404C203014093 @default.
- W2903854404 hasConceptScore W2903854404C2778062946 @default.
- W2903854404 hasConceptScore W2903854404C2778128430 @default.
- W2903854404 hasConceptScore W2903854404C2778494684 @default.
- W2903854404 hasConceptScore W2903854404C2780014101 @default.
- W2903854404 hasConceptScore W2903854404C2780898057 @default.
- W2903854404 hasConceptScore W2903854404C45189115 @default.
- W2903854404 hasConceptScore W2903854404C49105822 @default.
- W2903854404 hasConceptScore W2903854404C55493867 @default.
- W2903854404 hasConceptScore W2903854404C71924100 @default.
- W2903854404 hasConceptScore W2903854404C86803240 @default.
- W2903854404 hasIssue "1" @default.
- W2903854404 hasLocation W29038544041 @default.
- W2903854404 hasLocation W29038544042 @default.
- W2903854404 hasOpenAccess W2903854404 @default.
- W2903854404 hasPrimaryLocation W29038544041 @default.
- W2903854404 hasRelatedWork W1547502251 @default.
- W2903854404 hasRelatedWork W2017225095 @default.