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• W2903889765 startingPage "131" @default.
• W2903889765 abstract "Since their discovery as the etiologic agents of cervical cancer in the mid-1970s, human papillomaviruses (HPVs) have been linked with a growing number of epithelial-derived tumors, including head and neck squamous cell carcinomas. HPV demonstrates a particular predilection for causing tumors of the oropharynx, with the majority of cases involving infection with high-oncogenic risk HPV-16. People living with HIV are at increased risk of infection with HPV- and HPV-related oral complications even with adequate control of their HIV infection with antiretroviral therapy. In this chapter, we discuss the molecular mechanisms that underlie HPV-mediated oncogenesis in the oropharynx. We also describe the progress that has been made in understanding the epidemiology of oral HPV infection and the determinants of oral HPV-related pathology. Finally, we examine what can be done to treat and prevent oral HPV infection, benign lesions, and cancer, particularly in the context of the HIV-positive patient." @default.
• W2903889765 created "2018-12-22" @default.
• W2903889765 creator A5065401474 @default.
• W2903889765 creator A5067268074 @default.
• W2903889765 date "2018-12-07" @default.
• W2903889765 modified "2023-10-16" @default.
• W2903889765 title "HPV-Associated Oropharyngeal Cancer in the HIV/AIDS Patient" @default.
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