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- W2903958232 endingPage "100732" @default.
- W2903958232 startingPage "100732" @default.
- W2903958232 abstract "In mammals successful rearing imposes a cost on later reproductive fitness specifically on the mother creating the potential for parental conflict. Loss of function of three imprinted genes in the dam results in deficits in maternal care suggesting that, like maternal nutrients, maternal care is a resource over which the parental genomes are in conflict. The induction of maternal care is a complex, highly regulated process and it is unsurprising that many gene disruptions and environmental adversities result in maternal care deficits. However, recent compelling evidence for a more purposeful imprinting phenomenon comes from observing alterations in the mother’s behaviour when expression of the imprinted genes Phlda2 and Peg3 has been manipulated solely in the offspring. This explicit demonstration that imprinted genes expressed in the offspring influence maternal behaviour lends significant weight to the hypothesis that maternal care is a resource that has been manipulated by the paternal genome." @default.
- W2903958232 created "2018-12-22" @default.
- W2903958232 creator A5045539067 @default.
- W2903958232 creator A5050668873 @default.
- W2903958232 creator A5057950464 @default.
- W2903958232 creator A5064745330 @default.
- W2903958232 date "2019-04-01" @default.
- W2903958232 modified "2023-09-30" @default.
- W2903958232 title "Imprinted genes influencing the quality of maternal care" @default.
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