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• W2903977210 abstract "Liver ischemia/reperfusion (I/R) injury is a major complication of hepatic surgery and transplantation. It is one of the leading causes of morbidity and mortality because of post-surgery hepatic dysfunction. Several studies have suggested different mechanisms are involved in the pathogenesis of I/R injury in the liver that includes oxidative stress, inflammation, mitochondria dysfunction, liver Kupffer cells (KCs) activation, vascular cell adhesion molecule overexpression, and facilitation of polymorphonuclear neutrophil injury. Curcumin is a natural product extracted from Curcuma longa that is known to suppress these pathways and as a result reduces liver ischemia-reperfusion injury. This paper gives an overview of the protective effects of curcumin against I/R injury in the liver and discusses the studies that have linked biological functions of curcumin with liver I/R injury improvement." @default.
• W2903977210 created "2018-12-22" @default.
• W2903977210 creator A5002636312 @default.
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• W2903977210 creator A5064495299 @default.
• W2903977210 creator A5066860370 @default.
• W2903977210 creator A5080103146 @default.
• W2903977210 date "2019-03-01" @default.
• W2903977210 modified "2023-09-29" @default.
• W2903977210 title "Protective effects of curcumin against ischemia-reperfusion injury in the liver" @default.
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