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• W2904051372 abstract "Adrenocortical carcinoma (ACC) is an aggressive form of cancer that originates in the cortex of the adrenal gland; the incidence of ACC is 1.5 to 2 cases per million people per year. ACCs are rare and mostly sporadic. A small proportion of ACC cases are associated with hereditary cancer syndromes. Here, we present a case of ACC with a pathogenic heterozygous germline deletion in CHEK2 (c.1100delC). This is, to our knowledge, the first report of a patient with ACC associated with a CHEK2 germline deletion." @default.
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• W2904051372 date "2018-12-12" @default.
• W2904051372 modified "2023-09-26" @default.
• W2904051372 title "Case Report of an Adrenocortical Carcinoma Associated With Germline CHEK2 Mutation" @default.
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• W2904051372 doi "https://doi.org/10.1210/js.2018-00343" @default.
• W2904051372 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6320243" @default.
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