FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904064013> ?p ?o ?g. }

• W2904064013 abstract "ABSTRACT This investigation evaluated the reliability and validity of the 6‐Minute Walk Test (6MWT) in patients with pediatric hypophosphatasia (HPP). Children (aged 6 to 12 years; n = 11), adolescents (13 to 17 years; n = 4), and adults (18 to 65 years; n = 9) completed the 6MWT at screening and baseline in two clinical studies of asfotase alfa. Test‐retest reliability of the 6MWT, evaluated with Pearson's correlation coefficients ( r ) for screening versus baseline, was high for children ( r = 0.95; p < 0.0001), adolescents ( r = 0.81; p = 0.125), and adults ( r = 0.94; p = 0.0001). The most conservative minimal clinically important differences, estimated using distribution‐based methods, were 31 m (children and adults) and 43 m (adolescents). In children, the 6MWT correlated significantly with scores on measures of skeletal disease, which included the Radiographic Global Impression of Change scale ( r = 0.50; p < 0.0001) and the Rickets Severity Scale ( r = −0.78; p < 0.0001), such that distance walked increased as the severity of skeletal disease decreased. Significant ( p < 0.0001) correlations with the 6MWT distance walked were also observed for children with scores on parent‐reported measures of disability ( r = −0.67), ability to function in activities of daily living ( r = 0.71 to 0.77), and parent‐reported measures of pain ( r = −0.39). In adolescents and adults, 6MWT distance walked correlated significantly ( p < 0.05) with measures of lower extremity function ( r = 0.83 and 0.60, respectively), total pain severity ( r = −0.41 and −0.36, respectively), and total pain interference ( r = −0.41 and −0.49, respectively). Collectively, these data indicate that the 6MWT is a reliable, valid measure of physical functioning in patients with pediatric HPP. © 2018 The Authors. JBMR Plus Published by Wiley Periodicals, Inc. on behalf of the American Society for Bone and Mineral Research." @default.
• W2904064013 created "2018-12-22" @default.
• W2904064013 creator A5005389407 @default.
• W2904064013 creator A5035870078 @default.
• W2904064013 creator A5038346531 @default.
• W2904064013 creator A5059931388 @default.
• W2904064013 creator A5082943519 @default.
• W2904064013 creator A5086076842 @default.
• W2904064013 date "2019-03-01" @default.
• W2904064013 modified "2023-10-18" @default.
• W2904064013 title "Reliability and Validity of the 6-Minute Walk Test in Hypophosphatasia" @default.
• W2904064013 cites W1876622243 @default.
• W2904064013 cites W1951817210 @default.
• W2904064013 cites W1970108177 @default.
• W2904064013 cites W1971516537 @default.
• W2904064013 cites W1973772928 @default.
• W2904064013 cites W1983378915 @default.
• W2904064013 cites W1987322136 @default.
• W2904064013 cites W1988043493 @default.
• W2904064013 cites W1993027304 @default.
• W2904064013 cites W2004890638 @default.
• W2904064013 cites W2005866851 @default.
• W2904064013 cites W2006331513 @default.
• W2904064013 cites W2018442240 @default.
• W2904064013 cites W2019792829 @default.
• W2904064013 cites W2023155405 @default.
• W2904064013 cites W2035947437 @default.
• W2904064013 cites W2037559753 @default.
• W2904064013 cites W2041114293 @default.
• W2904064013 cites W2041158844 @default.
• W2904064013 cites W2043785457 @default.
• W2904064013 cites W2053045761 @default.
• W2904064013 cites W2058459242 @default.
• W2904064013 cites W2063869981 @default.
• W2904064013 cites W2064871164 @default.
• W2904064013 cites W2065834960 @default.
• W2904064013 cites W2065872793 @default.
• W2904064013 cites W2068865337 @default.
• W2904064013 cites W2081817259 @default.
• W2904064013 cites W2100799766 @default.
• W2904064013 cites W2100848202 @default.
• W2904064013 cites W2101800013 @default.
• W2904064013 cites W2102251663 @default.
• W2904064013 cites W2103037586 @default.
• W2904064013 cites W2107554167 @default.
• W2904064013 cites W2108075643 @default.
• W2904064013 cites W2108458974 @default.
• W2904064013 cites W2119013995 @default.
• W2904064013 cites W2127364492 @default.
• W2904064013 cites W2133176696 @default.
• W2904064013 cites W2136255603 @default.
• W2904064013 cites W2137030705 @default.
• W2904064013 cites W2172486723 @default.
• W2904064013 cites W2234725241 @default.
• W2904064013 cites W2275854596 @default.
• W2904064013 cites W2298155301 @default.
• W2904064013 cites W2309887726 @default.
• W2904064013 cites W2320909684 @default.
• W2904064013 cites W2402868861 @default.
• W2904064013 cites W2403519468 @default.
• W2904064013 cites W2434163946 @default.
• W2904064013 cites W2437385547 @default.
• W2904064013 cites W2478685917 @default.
• W2904064013 cites W2484593104 @default.
• W2904064013 cites W2489042166 @default.
• W2904064013 cites W2608228049 @default.
• W2904064013 cites W2761204945 @default.
• W2904064013 cites W2767595126 @default.
• W2904064013 cites W2769584219 @default.
• W2904064013 cites W2782092346 @default.
• W2904064013 cites W3104006481 @default.
• W2904064013 cites W4239662035 @default.
• W2904064013 cites W4245666729 @default.
• W2904064013 cites W4248820996 @default.
• W2904064013 doi "https://doi.org/10.1002/jbm4.10131" @default.
• W2904064013 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6636775" @default.
• W2904064013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31346563" @default.
• W2904064013 hasPublicationYear "2019" @default.
• W2904064013 type Work @default.
• W2904064013 sameAs 2904064013 @default.
• W2904064013 citedByCount "8" @default.
• W2904064013 countsByYear W29040640132020 @default.
• W2904064013 countsByYear W29040640132021 @default.
• W2904064013 countsByYear W29040640132022 @default.
• W2904064013 countsByYear W29040640132023 @default.
• W2904064013 crossrefType "journal-article" @default.
• W2904064013 hasAuthorship W2904064013A5005389407 @default.
• W2904064013 hasAuthorship W2904064013A5035870078 @default.
• W2904064013 hasAuthorship W2904064013A5038346531 @default.
• W2904064013 hasAuthorship W2904064013A5059931388 @default.
• W2904064013 hasAuthorship W2904064013A5082943519 @default.
• W2904064013 hasAuthorship W2904064013A5086076842 @default.
• W2904064013 hasBestOaLocation W29040640131 @default.
• W2904064013 hasConcept C126322002 @default.
• W2904064013 hasConcept C160160445 @default.
• W2904064013 hasConcept C181199279 @default.
• W2904064013 hasConcept C185592680 @default.
• W2904064013 hasConcept C1862650 @default.
• W2904064013 hasConcept C187212893 @default.
• W2904064013 hasConcept C2778471162 @default.

• next