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- W2904136165 abstract "The human immune system naturally makes antibodies to protect us from infection. By using new technologies such as genetic engineering, monoclonal antibody technology has revolutionised the treatment of some human diseases, however have failed in many intractable diseases. This thesis describes genetic engineering approaches to improve the function and efficacy of antibodies and shows that such approaches can generate new forms that have improved potency of over 100-fold. This paves the way for the next generation of therapeutic monoclonal antibodies and biopharmaceuticals for the treatment of intractable and incurable human diseases." @default.
- W2904136165 created "2018-12-22" @default.
- W2904136165 creator A5019611893 @default.
- W2904136165 date "2018-12-12" @default.
- W2904136165 modified "2023-09-27" @default.
- W2904136165 title "Novel Approaches for the Generation of Human Antibody Therapeutics by IgG Hinge and Fc Engineering" @default.
- W2904136165 doi "https://doi.org/10.26180/5c1195a694e95" @default.
- W2904136165 hasPublicationYear "2018" @default.
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