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- W2904153925 abstract "2,3-Annulated indoles exhibit a broad spectrum of biological activities. Various annulation strategies are applied to generate these scaffolds from prefunctionalized aniline or indole derivatives. Only a few methodologies allow the direct annulation of indole itself, often associated with regioselectivity issues or restrictions on available substitution patterns. More recently, ruthenium-catalyzed cascade transformations of readily available propargyl alcohols have been applied to the selective synthesis of various cyclo[b]fused indoles directly from indole. These efficient processes provide rapid access to intricate molecular structures from simple starting materials and facilitate the preparation of drug-like molecules." @default.
- W2904153925 created "2018-12-22" @default.
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- W2904153925 date "2018-12-13" @default.
- W2904153925 modified "2023-09-25" @default.
- W2904153925 title "Modern Annulation Strategies for the Synthesis of Cyclo[b]fused Indoles" @default.
- W2904153925 cites W2266873437 @default.
- W2904153925 doi "https://doi.org/10.1055/s-0037-1610336" @default.
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