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- W2904191776 abstract "Solitary fibrous tumour is a rare mesenchymal neoplasm with varied clinical behaviour and presenting symptoms. The pleura is a common site of initial presentation, but solitary fibrous tumours can occur in a variety of non-pleural soft tissue locations throughout the body. Although most typical solitary fibrous tumours present as localised disease and behave in an indolent fashion, malignant and dedifferentiated forms can act more aggressively, resulting in substantial morbidity and mortality. Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: a multicentre, single-arm, phase 2 trialTo our knowledge, this is the first trial of pazopanib for treatment of malignant solitary fibrous tumour showing activity in this patient group. The manageable toxicity profile and the activity shown by pazopanib suggests that this drug could be an option for systemic treatment of advanced malignant solitary fibrous tumour, and provides a benchmark for future trials. Full-Text PDF" @default.
- W2904191776 created "2018-12-22" @default.
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- W2904191776 date "2019-01-01" @default.
- W2904191776 modified "2023-10-12" @default.
- W2904191776 title "Anti-angiogenic therapy for malignant solitary fibrous tumour: validation through collaboration" @default.
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- W2904191776 doi "https://doi.org/10.1016/s1470-2045(18)30745-9" @default.
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