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- W2904200503 abstract "Although the traditional silicon-based microcantilever working with intrinsic piezoresistive effect has high sensitivity, it is easier to be broken in practical application because of its high elastic modulus. In this paper, we develop a piezoresistive microcantilever with a flexible polymide (PI) layer, whose Young's modulus is only about one-tenth of silicon oxide, as the top insulator of the single-crystalline silicon piezoresistor. The polymide-based piezoresistive microcantilever was fabricated on a SOI wafer and the experimental output voltage fluctuation of the fabricated microcantilevers in the phosphate buffered saline (PBS) solution is within 2μV at 3V bias voltage supply. Finally, a sensitive detection of abrin toxin was realized with a limit of detection of 30ng/mL (0.01M) by modifying the anti-abrin PcAb on the top gold surface of the microcantilever. Due to the fact that the fabrication process is compatible with CMOS, it provides a promising possibility to monolithically integrate the piezoresistive microcantilever biosensor with SOI CMOS circuits." @default.
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- W2904200503 date "2018-10-01" @default.
- W2904200503 modified "2023-09-23" @default.
- W2904200503 title "Detection of Abrin Using a Polymide-based Piezoresistive Microcantilever Biosensor" @default.
- W2904200503 cites W2027297288 @default.
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- W2904200503 doi "https://doi.org/10.1109/icsict.2018.8564879" @default.
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