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• W2904232472 abstract "Systemic therapy options have emerged for treatment of progressive, radioiodine-refractory differentiated thyroid carcinoma. Approved therapies that target tumor angiogenesis, lenvatinib and sorafenib, improve progression-free survival and, in an older subset, lenvatinib can prolong overall survival. Treatments based on targeting specific somatic genetic alterations are also available, which potentially also may prolong progression-free survival but are not yet approved for use by the Food and Drug Administration for this specific disease. More novel approaches that may benefit select patients include resensitization therapies that allow further radioiodine utilization and new immunotherapy concepts." @default.
• W2904232472 created "2018-12-22" @default.
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• W2904232472 date "2019-03-01" @default.
• W2904232472 modified "2023-10-18" @default.
• W2904232472 title "Novel Drug Treatments of Progressive Radioiodine-Refractory Differentiated Thyroid Cancer" @default.
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• W2904232472 doi "https://doi.org/10.1016/j.ecl.2018.10.009" @default.
• W2904232472 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30717907" @default.
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