FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904237721> ?p ?o ?g. }

• W2904237721 abstract "The aim of this study was to identify fibrosis-related serological surrogate outcome measures in patients with immunoglobulin G4-related disease (IgG4-RD). This was a clinical observational study of 72 patients with untreated IgG4-RD from four institutions in Japan. The serum concentrations of growth differentiation factor 15 (GDF-15), CCL2, hyaluronic acid (HA), amino-terminal propeptide of type III procollagen (PIIINP), and tissue inhibitor of metalloproteinases 1 (TIMP-1) were measured by enzyme-linked immunosorbent assays. The enhanced liver fibrosis (ELF) score was calculated from the TIMP-1, PIIINP, and HA values. We evaluated associations between the values of these biomarkers and laboratory data, the IgG4-RD responder index (IgG4-RD RI) score, and organ involvements. Compared with the 44 healthy controls, the patients with IgG4-RD showed significantly elevated serum concentrations of GDF-15, MCP-1, HA, PIIINP, and TIMP-1 and ELF scores. The patients’ serum concentrations of GDF-15, CCL2, HA, and TIMP-1 (but not PIIINP) were positively correlated with each other. Among them, serum GDF-15 most efficiently distinguished patients with IgG4-RD from healthy controls. Serum GDF-15 was not associated with the IgG4-RD RI score or the number of organ involvements but was independently associated with the presence of retroperitoneal fibrosis and with parotid gland involvement. We observed increased serological surrogate outcome measures of fibrosis in IgG4-RD. GDF-15 may precisely reflect the fibrotic degree in patients with IgG4-RD." @default.
• W2904237721 created "2018-12-22" @default.
• W2904237721 creator A5015568967 @default.
• W2904237721 creator A5022076444 @default.
• W2904237721 creator A5022125728 @default.
• W2904237721 creator A5024788322 @default.
• W2904237721 creator A5033993023 @default.
• W2904237721 creator A5035237919 @default.
• W2904237721 creator A5035694731 @default.
• W2904237721 creator A5035859888 @default.
• W2904237721 creator A5039472504 @default.
• W2904237721 creator A5043628933 @default.
• W2904237721 creator A5055846400 @default.
• W2904237721 creator A5056424845 @default.
• W2904237721 creator A5070326257 @default.
• W2904237721 creator A5084299259 @default.
• W2904237721 creator A5089657463 @default.
• W2904237721 creator A5091177614 @default.
• W2904237721 date "2018-12-01" @default.
• W2904237721 modified "2023-10-07" @default.
• W2904237721 title "Association of serum levels of fibrosis-related biomarkers with disease activity in patients with IgG4-related disease" @default.
• W2904237721 cites W1558382155 @default.
• W2904237721 cites W1891160624 @default.
• W2904237721 cites W1969015127 @default.
• W2904237721 cites W1969615927 @default.
• W2904237721 cites W1982216466 @default.
• W2904237721 cites W2001114333 @default.
• W2904237721 cites W2010033528 @default.
• W2904237721 cites W2010334618 @default.
• W2904237721 cites W2013324002 @default.
• W2904237721 cites W2021988356 @default.
• W2904237721 cites W2035995635 @default.
• W2904237721 cites W2039479642 @default.
• W2904237721 cites W2058203033 @default.
• W2904237721 cites W2075300336 @default.
• W2904237721 cites W2076205548 @default.
• W2904237721 cites W2084180340 @default.
• W2904237721 cites W2085111807 @default.
• W2904237721 cites W2104293075 @default.
• W2904237721 cites W2108218187 @default.
• W2904237721 cites W2108302885 @default.
• W2904237721 cites W2109560931 @default.
• W2904237721 cites W2115664066 @default.
• W2904237721 cites W2121514783 @default.
• W2904237721 cites W2143651115 @default.
• W2904237721 cites W2146616740 @default.
• W2904237721 cites W2151201247 @default.
• W2904237721 cites W2160347285 @default.
• W2904237721 cites W2160988692 @default.
• W2904237721 cites W2282063365 @default.
• W2904237721 cites W2293761297 @default.
• W2904237721 cites W2465812213 @default.
• W2904237721 cites W2532414666 @default.
• W2904237721 cites W2587193898 @default.
• W2904237721 cites W2621221129 @default.
• W2904237721 cites W2761072018 @default.
• W2904237721 cites W2773316649 @default.
• W2904237721 cites W3140754719 @default.
• W2904237721 cites W4244666018 @default.
• W2904237721 cites W4252135493 @default.
• W2904237721 doi "https://doi.org/10.1186/s13075-018-1777-7" @default.
• W2904237721 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6293522" @default.
• W2904237721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30547825" @default.
• W2904237721 hasPublicationYear "2018" @default.
• W2904237721 type Work @default.
• W2904237721 sameAs 2904237721 @default.
• W2904237721 citedByCount "13" @default.
• W2904237721 countsByYear W29042377212019 @default.
• W2904237721 countsByYear W29042377212020 @default.
• W2904237721 countsByYear W29042377212021 @default.
• W2904237721 countsByYear W29042377212022 @default.
• W2904237721 countsByYear W29042377212023 @default.
• W2904237721 crossrefType "journal-article" @default.
• W2904237721 hasAuthorship W2904237721A5015568967 @default.
• W2904237721 hasAuthorship W2904237721A5022076444 @default.
• W2904237721 hasAuthorship W2904237721A5022125728 @default.
• W2904237721 hasAuthorship W2904237721A5024788322 @default.
• W2904237721 hasAuthorship W2904237721A5033993023 @default.
• W2904237721 hasAuthorship W2904237721A5035237919 @default.
• W2904237721 hasAuthorship W2904237721A5035694731 @default.
• W2904237721 hasAuthorship W2904237721A5035859888 @default.
• W2904237721 hasAuthorship W2904237721A5039472504 @default.
• W2904237721 hasAuthorship W2904237721A5043628933 @default.
• W2904237721 hasAuthorship W2904237721A5055846400 @default.
• W2904237721 hasAuthorship W2904237721A5056424845 @default.
• W2904237721 hasAuthorship W2904237721A5070326257 @default.
• W2904237721 hasAuthorship W2904237721A5084299259 @default.
• W2904237721 hasAuthorship W2904237721A5089657463 @default.
• W2904237721 hasAuthorship W2904237721A5091177614 @default.
• W2904237721 hasBestOaLocation W29042377211 @default.
• W2904237721 hasConcept C105702510 @default.
• W2904237721 hasConcept C126322002 @default.
• W2904237721 hasConcept C142724271 @default.
• W2904237721 hasConcept C159654299 @default.
• W2904237721 hasConcept C198451711 @default.
• W2904237721 hasConcept C203014093 @default.
• W2904237721 hasConcept C2777529286 @default.
• W2904237721 hasConcept C2780224187 @default.
• W2904237721 hasConcept C2780559512 @default.
• W2904237721 hasConcept C45189115 @default.

• next