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- W2904257675 abstract "Abstract Photoacoustic (PA) imaging as a fast‐developing imaging technique has great potential in biomedical and clinical applications. It is a noninvasive imaging modality that depends on the light‐absorption coefficient of the imaged tissue and the injected PA‐imaging contrast agents. Furthermore, PA imaging provides superb contrast, super spatial resolution, and high penetrability and sensitivity to tissue functional characteristics by detecting the acoustic wave to construct PA images. In recent years, a series of PA‐imaging contrast agents are developed to improve the PA‐imaging performance in biomedical applications. Here, recent progress of PA contrast agents and their biomedical applications are outlined. PA contrast agents are classified according to their components and function, and gold nanocrystals, gold‐nanocrystal assembly, transition‐metal chalcogenides/MXene‐based nanomaterials, carbon‐based nanomaterials, other inorganic imaging agents, small organic molecules, semiconducting polymer nanoparticles, and nonlinear PA‐imaging contrast agents are discussed. The applications of PA contrast agents as biosensors (in the sensing of metal ions, pH, enzymes, temperature, hypoxia, reactive oxygen species, and reactive nitrogen species) and in bioimaging (lymph nodes, vasculature, tumors, and brain tissue) are discussed in detail. Finally, an outlook on the future research and investigation of PA‐imaging contrast agents and their significance in biomedical research is presented." @default.
- W2904257675 created "2018-12-22" @default.
- W2904257675 creator A5012902167 @default.
- W2904257675 creator A5018249388 @default.
- W2904257675 creator A5034175275 @default.
- W2904257675 creator A5044939329 @default.
- W2904257675 creator A5061908386 @default.
- W2904257675 date "2018-12-17" @default.
- W2904257675 modified "2023-10-15" @default.
- W2904257675 title "Photoacoustic Imaging: Contrast Agents and Their Biomedical Applications" @default.
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