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• W2904271368 abstract "A convenient method to access a broad variety of N-alkyl-(2,2,6,6)-tetramethylpiperidin-4-ol compounds is reported. The thermal treatment of a mixture of (2,2,6,6)-tetramethylpiperidin-4-ol and allyl or benzyl bromide derivatives gave the corresponding N–alkylated compounds in good yields while leaving the hydroxyl functional group intact. Whereas 40 h were needed to reach complete conversion, microwave irradiation allowed the reaction time to be reduced (20 min) and improved the yields in most cases." @default.
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• W2904271368 date "2019-01-01" @default.
• W2904271368 modified "2023-10-14" @default.
• W2904271368 title "General methodology for the chemoselective N-alkylation of (2,2,6,6)-tetramethylpiperidin-4-ol: Contribution of microwave irradiation" @default.
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• W2904271368 doi "https://doi.org/10.1016/j.tetlet.2018.12.020" @default.
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