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- W2904291465 abstract "This chapter describes the use of lenses obtained from rats as a model of cataractogenesis. At the molecular level, this is visualized as reduced activity of oxidative reductive enzymes such as aldose reductase and increased proteolysis of lens structural proteins including vimentin. In this chapter, protocols for assessment of these two pathways are presented. Specifically, this analysis shows a comparison of aldose reductase activity and vimentin cleavage in male and female rat lenses. This is because female rats are more susceptible to cataract formation compared to males." @default.
- W2904291465 created "2018-12-22" @default.
- W2904291465 creator A5012919903 @default.
- W2904291465 date "2018-12-11" @default.
- W2904291465 modified "2023-10-16" @default.
- W2904291465 title "A Rat Eye Lens Model of Cataract Formation" @default.
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- W2904291465 doi "https://doi.org/10.1007/978-1-4939-8994-2_30" @default.
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- W2904291465 hasPublicationYear "2018" @default.
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