Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904292543> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2904292543 abstract "Novel approaches to drug delivery and formulation using nanotechnology are revolutionizing the future of medicine. The application of nanotechnology in medicine is offering many exciting possibilities in healthcare. Engineered nanoparticles and conjugation of monoclonal antibodies with anticancer drug Docetaxel have the potential to revolutionize the diagnosis and the therapy of its diseases, particularly by targeted delivery of anticancer drugs and imaging contrast agents. Prostate cancer, the second most common cancer in men, represents one of the major epidemiological problems, especially for patients in the advanced age. There is a substantial interest in developing therapeutic options for treatment of prostate cancer based on use of nanocarriers with the conjugation of drug and antibody, to overcome the lack of specificity of conventional chemotherapeutic agents as well as for the early detection of precancerous and malignant lesions. In this article, we highlight on the recent development of bioconjugation of drug with nanotechnology strategies adopted for the management of prostate cancer. In particular, the combination of targeted and controlled-release polymer nanocarriers have worked against prostate specific membrane antigen, a promising targeted Docetaxel-loaded nanoparticles, which can be validated for use in the prostate cancer therapy. However, several limitations facing nanoparticle delivery to solid tumors, such as heterogeneity of intratumoural barriers and vasculature, cytotoxicity and or hypersensitivity reactions to currently available cancer nanomedicines, and the difficult in developing targeted nanoparticles with optimal biophysicochemical properties, should be still addressed for successful tumor eradication." @default.
- W2904292543 created "2018-12-22" @default.
- W2904292543 creator A5000738290 @default.
- W2904292543 creator A5014288848 @default.
- W2904292543 creator A5085733715 @default.
- W2904292543 date "2014-09-30" @default.
- W2904292543 modified "2023-09-26" @default.
- W2904292543 title "Monoclonal antibody conjugated Nanoparticles targeted to Prostate tumor cells" @default.
- W2904292543 doi "https://doi.org/10.30750/ijpbr.2.3.5" @default.
- W2904292543 hasPublicationYear "2014" @default.
- W2904292543 type Work @default.
- W2904292543 sameAs 2904292543 @default.
- W2904292543 citedByCount "0" @default.
- W2904292543 crossrefType "journal-article" @default.
- W2904292543 hasAuthorship W2904292543A5000738290 @default.
- W2904292543 hasAuthorship W2904292543A5014288848 @default.
- W2904292543 hasAuthorship W2904292543A5085733715 @default.
- W2904292543 hasBestOaLocation W29042925431 @default.
- W2904292543 hasConcept C121608353 @default.
- W2904292543 hasConcept C126322002 @default.
- W2904292543 hasConcept C126511603 @default.
- W2904292543 hasConcept C15083742 @default.
- W2904292543 hasConcept C155672457 @default.
- W2904292543 hasConcept C159654299 @default.
- W2904292543 hasConcept C171250308 @default.
- W2904292543 hasConcept C18150654 @default.
- W2904292543 hasConcept C192562407 @default.
- W2904292543 hasConcept C203014093 @default.
- W2904292543 hasConcept C2779820397 @default.
- W2904292543 hasConcept C2780035454 @default.
- W2904292543 hasConcept C2780192828 @default.
- W2904292543 hasConcept C2781190966 @default.
- W2904292543 hasConcept C2781230642 @default.
- W2904292543 hasConcept C502942594 @default.
- W2904292543 hasConcept C542903549 @default.
- W2904292543 hasConcept C71924100 @default.
- W2904292543 hasConcept C98274493 @default.
- W2904292543 hasConceptScore W2904292543C121608353 @default.
- W2904292543 hasConceptScore W2904292543C126322002 @default.
- W2904292543 hasConceptScore W2904292543C126511603 @default.
- W2904292543 hasConceptScore W2904292543C15083742 @default.
- W2904292543 hasConceptScore W2904292543C155672457 @default.
- W2904292543 hasConceptScore W2904292543C159654299 @default.
- W2904292543 hasConceptScore W2904292543C171250308 @default.
- W2904292543 hasConceptScore W2904292543C18150654 @default.
- W2904292543 hasConceptScore W2904292543C192562407 @default.
- W2904292543 hasConceptScore W2904292543C203014093 @default.
- W2904292543 hasConceptScore W2904292543C2779820397 @default.
- W2904292543 hasConceptScore W2904292543C2780035454 @default.
- W2904292543 hasConceptScore W2904292543C2780192828 @default.
- W2904292543 hasConceptScore W2904292543C2781190966 @default.
- W2904292543 hasConceptScore W2904292543C2781230642 @default.
- W2904292543 hasConceptScore W2904292543C502942594 @default.
- W2904292543 hasConceptScore W2904292543C542903549 @default.
- W2904292543 hasConceptScore W2904292543C71924100 @default.
- W2904292543 hasConceptScore W2904292543C98274493 @default.
- W2904292543 hasLocation W29042925431 @default.
- W2904292543 hasOpenAccess W2904292543 @default.
- W2904292543 hasPrimaryLocation W29042925431 @default.
- W2904292543 hasRelatedWork W1981412372 @default.
- W2904292543 hasRelatedWork W2007320138 @default.
- W2904292543 hasRelatedWork W2056051091 @default.
- W2904292543 hasRelatedWork W2074739302 @default.
- W2904292543 hasRelatedWork W2106972198 @default.
- W2904292543 hasRelatedWork W2110747936 @default.
- W2904292543 hasRelatedWork W2121862563 @default.
- W2904292543 hasRelatedWork W2192915678 @default.
- W2904292543 hasRelatedWork W2415528931 @default.
- W2904292543 hasRelatedWork W2549403371 @default.
- W2904292543 hasRelatedWork W2789383766 @default.
- W2904292543 hasRelatedWork W2970025169 @default.
- W2904292543 hasRelatedWork W2982425588 @default.
- W2904292543 hasRelatedWork W2983922218 @default.
- W2904292543 hasRelatedWork W3004672615 @default.
- W2904292543 hasRelatedWork W3015559193 @default.
- W2904292543 hasRelatedWork W3146237249 @default.
- W2904292543 hasRelatedWork W3166199315 @default.
- W2904292543 hasRelatedWork W3199731250 @default.
- W2904292543 hasRelatedWork W3204860351 @default.
- W2904292543 isParatext "false" @default.
- W2904292543 isRetracted "false" @default.
- W2904292543 magId "2904292543" @default.
- W2904292543 workType "article" @default.