Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904301855> ?p ?o ?g. }
- W2904301855 endingPage "88" @default.
- W2904301855 startingPage "82" @default.
- W2904301855 abstract "In this paper, nutriosomes (phospholipid vesicles associated with Nutriose® FM06) were modified to obtain new systems aimed at enhancing the efficacy of curcumin in counteracting malaria infection upon oral administration. Eudragit® L100, a pH-sensitive co-polymer, was added to these vesicles, thus obtaining eudragit-nutriosomes, to improve their in vivo performances. Liposomes without eudragit and nutriose were also prepared as a reference. Cryo-TEM images showed the formation of multicompartment vesicles, with mean diameter around 300 nm and highly negative zeta potential. Vesicles were stable in fluids mimicking the gastro-intestinal content due to the high phospholipid concentration and the presence of gastro-resistant eudragit and digestion-resistant nutriose. Eudragit-nutriosomes disclosed promising performances in vitro and in vivo: they maximized the ability of curcumin to counteract oxidative stress in intestinal cells (Caco-2), which presumably reinforced its systemic efficacy. Orally-administered curcumin-loaded eudragit-nutriosomes increased significantly the survival of malaria-infected mice relative to free curcumin-treated controls." @default.
- W2904301855 created "2018-12-22" @default.
- W2904301855 creator A5023387530 @default.
- W2904301855 creator A5029517468 @default.
- W2904301855 creator A5036635019 @default.
- W2904301855 creator A5037064508 @default.
- W2904301855 creator A5047133114 @default.
- W2904301855 creator A5056970164 @default.
- W2904301855 creator A5075686017 @default.
- W2904301855 creator A5084494863 @default.
- W2904301855 creator A5090841375 @default.
- W2904301855 date "2019-02-01" @default.
- W2904301855 modified "2023-10-03" @default.
- W2904301855 title "Nanoformulation of curcumin-loaded eudragit-nutriosomes to counteract malaria infection by a dual strategy: Improving antioxidant intestinal activity and systemic efficacy" @default.
- W2904301855 cites W1420784649 @default.
- W2904301855 cites W1966641706 @default.
- W2904301855 cites W1976194786 @default.
- W2904301855 cites W2001345375 @default.
- W2904301855 cites W2023182484 @default.
- W2904301855 cites W2033634323 @default.
- W2904301855 cites W2049014443 @default.
- W2904301855 cites W2066382988 @default.
- W2904301855 cites W2077166822 @default.
- W2904301855 cites W2077431908 @default.
- W2904301855 cites W2079178816 @default.
- W2904301855 cites W2080130381 @default.
- W2904301855 cites W2102192655 @default.
- W2904301855 cites W2114659729 @default.
- W2904301855 cites W2131357228 @default.
- W2904301855 cites W2157122000 @default.
- W2904301855 cites W2161145174 @default.
- W2904301855 cites W2161677504 @default.
- W2904301855 cites W2297128041 @default.
- W2904301855 cites W2474968789 @default.
- W2904301855 cites W2561224476 @default.
- W2904301855 cites W2564128267 @default.
- W2904301855 cites W2606614729 @default.
- W2904301855 cites W2609714015 @default.
- W2904301855 cites W2611265774 @default.
- W2904301855 cites W2746711110 @default.
- W2904301855 cites W2766083858 @default.
- W2904301855 cites W2772767082 @default.
- W2904301855 cites W2772926768 @default.
- W2904301855 cites W2776084588 @default.
- W2904301855 cites W2799300331 @default.
- W2904301855 cites W2799887168 @default.
- W2904301855 cites W2805897237 @default.
- W2904301855 doi "https://doi.org/10.1016/j.ijpharm.2018.11.073" @default.
- W2904301855 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30528634" @default.
- W2904301855 hasPublicationYear "2019" @default.
- W2904301855 type Work @default.
- W2904301855 sameAs 2904301855 @default.
- W2904301855 citedByCount "26" @default.
- W2904301855 countsByYear W29043018552019 @default.
- W2904301855 countsByYear W29043018552020 @default.
- W2904301855 countsByYear W29043018552021 @default.
- W2904301855 countsByYear W29043018552022 @default.
- W2904301855 countsByYear W29043018552023 @default.
- W2904301855 crossrefType "journal-article" @default.
- W2904301855 hasAuthorship W2904301855A5023387530 @default.
- W2904301855 hasAuthorship W2904301855A5029517468 @default.
- W2904301855 hasAuthorship W2904301855A5036635019 @default.
- W2904301855 hasAuthorship W2904301855A5037064508 @default.
- W2904301855 hasAuthorship W2904301855A5047133114 @default.
- W2904301855 hasAuthorship W2904301855A5056970164 @default.
- W2904301855 hasAuthorship W2904301855A5075686017 @default.
- W2904301855 hasAuthorship W2904301855A5084494863 @default.
- W2904301855 hasAuthorship W2904301855A5090841375 @default.
- W2904301855 hasConcept C130316041 @default.
- W2904301855 hasConcept C150903083 @default.
- W2904301855 hasConcept C155672457 @default.
- W2904301855 hasConcept C171250308 @default.
- W2904301855 hasConcept C185154212 @default.
- W2904301855 hasConcept C185592680 @default.
- W2904301855 hasConcept C192562407 @default.
- W2904301855 hasConcept C202751555 @default.
- W2904301855 hasConcept C207001950 @default.
- W2904301855 hasConcept C2777056448 @default.
- W2904301855 hasConcept C2777179404 @default.
- W2904301855 hasConcept C2778004101 @default.
- W2904301855 hasConcept C2778250585 @default.
- W2904301855 hasConcept C2778918659 @default.
- W2904301855 hasConcept C41625074 @default.
- W2904301855 hasConcept C501593827 @default.
- W2904301855 hasConcept C55493867 @default.
- W2904301855 hasConcept C71924100 @default.
- W2904301855 hasConcept C86181022 @default.
- W2904301855 hasConcept C86803240 @default.
- W2904301855 hasConcept C98274493 @default.
- W2904301855 hasConceptScore W2904301855C130316041 @default.
- W2904301855 hasConceptScore W2904301855C150903083 @default.
- W2904301855 hasConceptScore W2904301855C155672457 @default.
- W2904301855 hasConceptScore W2904301855C171250308 @default.
- W2904301855 hasConceptScore W2904301855C185154212 @default.
- W2904301855 hasConceptScore W2904301855C185592680 @default.
- W2904301855 hasConceptScore W2904301855C192562407 @default.
- W2904301855 hasConceptScore W2904301855C202751555 @default.
- W2904301855 hasConceptScore W2904301855C207001950 @default.