FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904310301> ?p ?o ?g. }

• W2904310301 abstract "Cytotoxic lymphocytes are increased in the airways of COPD patients. Whether this increase is driven primarily by the disease or by smoking is not clear, nor whether it correlates with the rate of decline in lung function. Bronchoscopy with BAL was performed in 52 subjects recruited from the longitudinal OLIN COPD study according to pre-determined criteria; 12 with COPD and a rapid decline in lung function (loss of FEV1 ≥ 60 ml/year), 10 with COPD and a non-rapid decline in lung function (loss of FEV1 ≤ 30 ml/year), 15 current and ex-smokers and 15 non-smokers with normal lung function. BAL lymphocyte subsets were determined using flow cytometry. In BAL fluid, the proportions of NK, iNKT and NKT-like cells all increased with pack-years. Within the COPD group, NK cells – but not iNKT or NKT-like cells – were significantly elevated also in subjects that had quit smoking. In contrast, current smoking was associated with a marked increase in iNKT and NKT-like cells but not in NK cells. Rate of lung function decline did not significantly affect any of the results. In summary, increased proportions of NK cells in BAL fluid were associated with COPD; iNKT and NKT-like cells with current smoking but not with COPD. Interestingly, NK cell percentages did not normalize in COPD subjects that had quit smoking, indicating that these cells might play a role in the continued disease progression seen in COPD even after smoking cessation. Clinicaltrials.gov identifier NCT02729220 ." @default.
• W2904310301 created "2018-12-22" @default.
• W2904310301 creator A5004221830 @default.
• W2904310301 creator A5032102375 @default.
• W2904310301 creator A5041939325 @default.
• W2904310301 creator A5046847705 @default.
• W2904310301 creator A5051672548 @default.
• W2904310301 creator A5061370731 @default.
• W2904310301 creator A5088331171 @default.
• W2904310301 date "2018-12-01" @default.
• W2904310301 modified "2023-10-14" @default.
• W2904310301 title "Cytotoxic lymphocytes in COPD airways: increased NK cells associated with disease, iNKT and NKT-like cells with current smoking" @default.
• W2904310301 cites W1538172952 @default.
• W2904310301 cites W1577058762 @default.
• W2904310301 cites W1702899070 @default.
• W2904310301 cites W2009042755 @default.
• W2904310301 cites W2013250552 @default.
• W2904310301 cites W2018280795 @default.
• W2904310301 cites W2032922046 @default.
• W2904310301 cites W2036327819 @default.
• W2904310301 cites W2037964449 @default.
• W2904310301 cites W2055309245 @default.
• W2904310301 cites W2069079702 @default.
• W2904310301 cites W2069307976 @default.
• W2904310301 cites W2084896616 @default.
• W2904310301 cites W2104578295 @default.
• W2904310301 cites W2108550035 @default.
• W2904310301 cites W2109708577 @default.
• W2904310301 cites W2114487151 @default.
• W2904310301 cites W2127327473 @default.
• W2904310301 cites W2139566553 @default.
• W2904310301 cites W2151757809 @default.
• W2904310301 cites W2164513774 @default.
• W2904310301 cites W2167493710 @default.
• W2904310301 cites W2169328623 @default.
• W2904310301 cites W2267939677 @default.
• W2904310301 cites W2276658880 @default.
• W2904310301 cites W2312668631 @default.
• W2904310301 cites W2583265473 @default.
• W2904310301 cites W2604596332 @default.
• W2904310301 cites W2776904990 @default.
• W2904310301 cites W2800567595 @default.
• W2904310301 doi "https://doi.org/10.1186/s12931-018-0940-7" @default.
• W2904310301 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6286566" @default.
• W2904310301 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30526599" @default.
• W2904310301 hasPublicationYear "2018" @default.
• W2904310301 type Work @default.
• W2904310301 sameAs 2904310301 @default.
• W2904310301 citedByCount "13" @default.
• W2904310301 countsByYear W29043103012019 @default.
• W2904310301 countsByYear W29043103012020 @default.
• W2904310301 countsByYear W29043103012021 @default.
• W2904310301 countsByYear W29043103012022 @default.
• W2904310301 countsByYear W29043103012023 @default.
• W2904310301 crossrefType "journal-article" @default.
• W2904310301 hasAuthorship W2904310301A5004221830 @default.
• W2904310301 hasAuthorship W2904310301A5032102375 @default.
• W2904310301 hasAuthorship W2904310301A5041939325 @default.
• W2904310301 hasAuthorship W2904310301A5046847705 @default.
• W2904310301 hasAuthorship W2904310301A5051672548 @default.
• W2904310301 hasAuthorship W2904310301A5061370731 @default.
• W2904310301 hasAuthorship W2904310301A5088331171 @default.
• W2904310301 hasBestOaLocation W29043103011 @default.
• W2904310301 hasConcept C126322002 @default.
• W2904310301 hasConcept C139563560 @default.
• W2904310301 hasConcept C142724271 @default.
• W2904310301 hasConcept C154317977 @default.
• W2904310301 hasConcept C202751555 @default.
• W2904310301 hasConcept C203014093 @default.
• W2904310301 hasConcept C2776090121 @default.
• W2904310301 hasConcept C2776780178 @default.
• W2904310301 hasConcept C2777714996 @default.
• W2904310301 hasConcept C2777843972 @default.
• W2904310301 hasConcept C55493867 @default.
• W2904310301 hasConcept C71924100 @default.
• W2904310301 hasConcept C86803240 @default.
• W2904310301 hasConcept C8891405 @default.
• W2904310301 hasConceptScore W2904310301C126322002 @default.
• W2904310301 hasConceptScore W2904310301C139563560 @default.
• W2904310301 hasConceptScore W2904310301C142724271 @default.
• W2904310301 hasConceptScore W2904310301C154317977 @default.
• W2904310301 hasConceptScore W2904310301C202751555 @default.
• W2904310301 hasConceptScore W2904310301C203014093 @default.
• W2904310301 hasConceptScore W2904310301C2776090121 @default.
• W2904310301 hasConceptScore W2904310301C2776780178 @default.
• W2904310301 hasConceptScore W2904310301C2777714996 @default.
• W2904310301 hasConceptScore W2904310301C2777843972 @default.
• W2904310301 hasConceptScore W2904310301C55493867 @default.
• W2904310301 hasConceptScore W2904310301C71924100 @default.
• W2904310301 hasConceptScore W2904310301C86803240 @default.
• W2904310301 hasConceptScore W2904310301C8891405 @default.
• W2904310301 hasFunder F4320322169 @default.
• W2904310301 hasFunder F4320322971 @default.
• W2904310301 hasFunder F4320323656 @default.
• W2904310301 hasIssue "1" @default.
• W2904310301 hasLocation W29043103011 @default.
• W2904310301 hasLocation W29043103012 @default.
• W2904310301 hasLocation W29043103013 @default.
• W2904310301 hasLocation W29043103014 @default.
• W2904310301 hasLocation W29043103015 @default.

• next