Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904322265> ?p ?o ?g. }
- W2904322265 endingPage "268" @default.
- W2904322265 startingPage "256" @default.
- W2904322265 abstract "The relationship between borderline personality disorder (BPD) and bipolar II disorder (BIP-II) is disputed but understudied. Here, we investigated brain glucose metabolism in these patient groups and healthy control subjects (HCs).Sixty-five subjects, 22 BPD (19 females), 22 BIP-II (17 females), and 21 HC (14 females), were examined using 2-deoxy-2[18F]-fluoro-d-glucose positron-emission tomography (PET) scanning. Only patients without reciprocal comorbidity were recruited; BPD participants without bipolar spectrum pathology; BIP-II participants without cluster A/B personality pathology. Groups were compared pairwise. Associations with mood state and childhood trauma were analyzed.Both patient groups exhibited hypometabolism compared with HCs in insula, brainstem, and frontal white matter. Additionally, BPD patients showed hypometabolism in hypothalamus, midbrain, and striatum; BIP-II patients in cerebellum. Uncorrected analyses showed cortical areas of higher metabolism in BIP-II than BPD, and associations with clinical variables differed between the groups.Reduced metabolism in the insula regions was shown in both disorders, suggesting shared pathophysiological mechanisms. The observed patterns of altered metabolism specific to each patient group, as well as the uncorrected results, may also suggest differential pathophysiology. However, these latter findings must be interpreted cautiously given the non-significant corrected results in the direct comparison between the disorders." @default.
- W2904322265 created "2018-12-22" @default.
- W2904322265 creator A5006003777 @default.
- W2904322265 creator A5011488569 @default.
- W2904322265 creator A5032364836 @default.
- W2904322265 creator A5036872905 @default.
- W2904322265 creator A5056008712 @default.
- W2904322265 creator A5070831538 @default.
- W2904322265 creator A5073324220 @default.
- W2904322265 creator A5076453721 @default.
- W2904322265 creator A5076456685 @default.
- W2904322265 creator A5080420774 @default.
- W2904322265 date "2019-01-06" @default.
- W2904322265 modified "2023-10-18" @default.
- W2904322265 title "Patterns of altered regional brain glucose metabolism in borderline personality disorder and bipolar <scp>II</scp> disorder" @default.
- W2904322265 cites W1605499779 @default.
- W2904322265 cites W181278426 @default.
- W2904322265 cites W1863427091 @default.
- W2904322265 cites W1978412297 @default.
- W2904322265 cites W1983927699 @default.
- W2904322265 cites W1987646763 @default.
- W2904322265 cites W1994605917 @default.
- W2904322265 cites W1994950269 @default.
- W2904322265 cites W1997316972 @default.
- W2904322265 cites W1997659373 @default.
- W2904322265 cites W2009606887 @default.
- W2904322265 cites W2013567461 @default.
- W2904322265 cites W2032602740 @default.
- W2904322265 cites W2034413695 @default.
- W2904322265 cites W2048681789 @default.
- W2904322265 cites W2052924704 @default.
- W2904322265 cites W2062264991 @default.
- W2904322265 cites W2065170383 @default.
- W2904322265 cites W2066191163 @default.
- W2904322265 cites W2068567001 @default.
- W2904322265 cites W2081658958 @default.
- W2904322265 cites W2089858495 @default.
- W2904322265 cites W2101062774 @default.
- W2904322265 cites W2106324685 @default.
- W2904322265 cites W2117650446 @default.
- W2904322265 cites W2119195417 @default.
- W2904322265 cites W2120654343 @default.
- W2904322265 cites W2131823335 @default.
- W2904322265 cites W2144538553 @default.
- W2904322265 cites W2148854507 @default.
- W2904322265 cites W2148922273 @default.
- W2904322265 cites W2152074896 @default.
- W2904322265 cites W2163559749 @default.
- W2904322265 cites W2167659819 @default.
- W2904322265 cites W2169366712 @default.
- W2904322265 cites W2171187401 @default.
- W2904322265 cites W2290190425 @default.
- W2904322265 cites W2469577751 @default.
- W2904322265 cites W2486216918 @default.
- W2904322265 cites W2524456233 @default.
- W2904322265 cites W2606545734 @default.
- W2904322265 cites W2775556590 @default.
- W2904322265 cites W2782016155 @default.
- W2904322265 cites W2783427306 @default.
- W2904322265 cites W4313634962 @default.
- W2904322265 doi "https://doi.org/10.1111/acps.12997" @default.
- W2904322265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30552759" @default.
- W2904322265 hasPublicationYear "2019" @default.
- W2904322265 type Work @default.
- W2904322265 sameAs 2904322265 @default.
- W2904322265 citedByCount "9" @default.
- W2904322265 countsByYear W29043222652019 @default.
- W2904322265 countsByYear W29043222652020 @default.
- W2904322265 countsByYear W29043222652021 @default.
- W2904322265 crossrefType "journal-article" @default.
- W2904322265 hasAuthorship W2904322265A5006003777 @default.
- W2904322265 hasAuthorship W2904322265A5011488569 @default.
- W2904322265 hasAuthorship W2904322265A5032364836 @default.
- W2904322265 hasAuthorship W2904322265A5036872905 @default.
- W2904322265 hasAuthorship W2904322265A5056008712 @default.
- W2904322265 hasAuthorship W2904322265A5070831538 @default.
- W2904322265 hasAuthorship W2904322265A5073324220 @default.
- W2904322265 hasAuthorship W2904322265A5076453721 @default.
- W2904322265 hasAuthorship W2904322265A5076456685 @default.
- W2904322265 hasAuthorship W2904322265A5080420774 @default.
- W2904322265 hasConcept C10162356 @default.
- W2904322265 hasConcept C104996578 @default.
- W2904322265 hasConcept C118552586 @default.
- W2904322265 hasConcept C126322002 @default.
- W2904322265 hasConcept C126838900 @default.
- W2904322265 hasConcept C134018914 @default.
- W2904322265 hasConcept C143409427 @default.
- W2904322265 hasConcept C15744967 @default.
- W2904322265 hasConcept C169760540 @default.
- W2904322265 hasConcept C2776174506 @default.
- W2904322265 hasConcept C2776394216 @default.
- W2904322265 hasConcept C2776809841 @default.
- W2904322265 hasConcept C2777134132 @default.
- W2904322265 hasConcept C2780600973 @default.
- W2904322265 hasConcept C2780733359 @default.
- W2904322265 hasConcept C2781192897 @default.
- W2904322265 hasConcept C558461103 @default.
- W2904322265 hasConcept C71924100 @default.