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• W2904362486 abstract "Abstract Background Clinicians and researchers commonly use global cognitive assessments to screen for impairment. Currently there are no published studies directly comparing the sensitivity and specificity of the Montreal Cognitive Assessment and Mattis Dementia Rating Scale‐2 in PD. The objective of this study was to identify the relative sensitivity and specificity of the Montreal Cognitive Assessment and Mattis Dementia Rating Scale‐2 in PD. Methods The Montreal Cognitive Assessment and Mattis Dementia Rating Scale‐2 were administered to training and validation cohorts. Cutoff scores were determined within the training cohort (n = 85) to optimize sensitivity and specificity for cognitive impairment and were applied to an independent validation cohort (n = 521). Results The Montreal Cognitive Assessment was consistently sensitive across training and validation cohorts (90.0% and 80.3%, respectively), whereas the Mattis Dementia Rating Scale‐2 was not (87.5% and 60.3%, respectively). In individual domains, the Montreal Cognitive Assessment remained sensitive to memory and visuospatial impairments (91.9% and 87.8%, respectively), whereas the Mattis Dementia Rating Scale‐2 was sensitive to executive impairments (86.2%). Conclusion The Montreal Cognitive Assessment and Mattis Dementia Rating Scale‐2 demonstrated individual strengths. Future work should focus on developing domain‐specific cognitive screening tools for PD. © 2018 International Parkinson and Movement Disorder Society" @default.
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• W2904362486 date "2018-12-10" @default.
• W2904362486 modified "2023-10-15" @default.
• W2904362486 title "Comparative sensitivity of the MoCA and Mattis Dementia Rating Scale‐2 in Parkinson's disease" @default.
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• W2904362486 doi "https://doi.org/10.1002/mds.27575" @default.
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