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• W2904365791 abstract "Abstract Increasing evidence links disorders of consciousness (DOC) with disruptions in functional connectivity between distant brain areas. However, to which extent the balance of brain network segregation and integration is modified in DOC patients remains unclear. Using high-density electroencephalography (EEG), the objective of our study was to characterize the local and global topological changes of DOC patients’ functional brain networks. Resting state high-density-EEG data were collected and analyzed from 82 participants: 61 DOC patients recovering from coma with various levels of consciousness (EMCS (n=6), MCS+ (n=29), MCS- (n=17) and UWS (n=9)), and 21 healthy subjects (i.e., controls). Functional brain networks in five different EEG frequency bands and the broadband signal were estimated using an EEG connectivity approach at the source level. Graph theory-based analyses were used to evaluate group differences between healthy volunteers and patient groups. Results showed that networks in DOC patients are characterized by impaired global information processing (network integration) and increased local information processing (network segregation) as compared to controls. The large-scale functional brain networks had integration decreasing with lower level of consciousness." @default.
• W2904365791 created "2018-12-22" @default.
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• W2904365791 date "2018-12-13" @default.
• W2904365791 modified "2023-09-23" @default.
• W2904365791 title "Decreased integration of EEG source-space networks in disorders of consciousness" @default.
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• W2904365791 doi "https://doi.org/10.1101/493395" @default.
• W2904365791 hasPublicationYear "2018" @default.
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