Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904367039> ?p ?o ?g. }
- W2904367039 endingPage "4298" @default.
- W2904367039 startingPage "4298" @default.
- W2904367039 abstract "A biosensor based on an etched Fiber Bragg Grating (EFBG) for thrombin detection is reported. The sensing system is based on a Fiber Bragg Grating (FBG) with a Bragg wavelength of 1550 nm, wet-etched in hydrofluoric acid (HF) for ~27 min, to achieve sensitivity to a refractive index (RI) of 17.4 nm/RIU (refractive index unit). Subsequently, in order to perform a selective detection of thrombin, the EFBG has been functionalized with silane-coupling agent 3-(aminopropyl)triethoxysilane (APTES) and a cross-linker, glutaraldehyde, for the immobilization of thrombin-binding aptamer. The biosensor has been validated for thrombin detection in concentrations ranging from 10 nM to 80 nM. The proposed sensor presents advantages with respect to other sensor configurations, based on plasmonic resonant tilted FBG or Long Period Grating (LPG), for thrombin detection. Firstly, fabricating an EFBG only requires chemical etching. Moreover, the functionalization method used in this study (silanization) allows the avoidance of complicated and expensive fabrications, such as thin film sputtering or chemical vapor deposition. Due to their characteristics, EFBG sensors are easier to multiplex and can be used in vivo. This opens new possibilities for the detection of thrombin in clinical settings." @default.
- W2904367039 created "2018-12-22" @default.
- W2904367039 creator A5023197214 @default.
- W2904367039 creator A5027737990 @default.
- W2904367039 creator A5029324921 @default.
- W2904367039 creator A5031565471 @default.
- W2904367039 creator A5032369315 @default.
- W2904367039 creator A5048155148 @default.
- W2904367039 creator A5052461783 @default.
- W2904367039 creator A5054769205 @default.
- W2904367039 date "2018-12-06" @default.
- W2904367039 modified "2023-10-11" @default.
- W2904367039 title "Etched Fiber Bragg Grating Biosensor Functionalized with Aptamers for Detection of Thrombin" @default.
- W2904367039 cites W1540927818 @default.
- W2904367039 cites W1964858690 @default.
- W2904367039 cites W1966333651 @default.
- W2904367039 cites W1984668005 @default.
- W2904367039 cites W1986024675 @default.
- W2904367039 cites W1986264670 @default.
- W2904367039 cites W1988638333 @default.
- W2904367039 cites W1999934045 @default.
- W2904367039 cites W2003712697 @default.
- W2904367039 cites W2014048114 @default.
- W2904367039 cites W2019042121 @default.
- W2904367039 cites W2019764635 @default.
- W2904367039 cites W2024546400 @default.
- W2904367039 cites W2028403374 @default.
- W2904367039 cites W2050344729 @default.
- W2904367039 cites W2055721693 @default.
- W2904367039 cites W2060689896 @default.
- W2904367039 cites W2064219521 @default.
- W2904367039 cites W2079923028 @default.
- W2904367039 cites W2086052136 @default.
- W2904367039 cites W2086962500 @default.
- W2904367039 cites W2095696503 @default.
- W2904367039 cites W2101904716 @default.
- W2904367039 cites W2106738667 @default.
- W2904367039 cites W2121554624 @default.
- W2904367039 cites W2142851080 @default.
- W2904367039 cites W2159355892 @default.
- W2904367039 cites W2163721501 @default.
- W2904367039 cites W2169089713 @default.
- W2904367039 cites W2172057454 @default.
- W2904367039 cites W2266271169 @default.
- W2904367039 cites W2276231667 @default.
- W2904367039 cites W2310900516 @default.
- W2904367039 cites W2345404588 @default.
- W2904367039 cites W2510896217 @default.
- W2904367039 cites W2519441080 @default.
- W2904367039 cites W2564201454 @default.
- W2904367039 cites W2591987431 @default.
- W2904367039 cites W2623475751 @default.
- W2904367039 cites W2733149799 @default.
- W2904367039 cites W2765393924 @default.
- W2904367039 cites W2766940139 @default.
- W2904367039 cites W2767236937 @default.
- W2904367039 cites W2779117235 @default.
- W2904367039 cites W2800037878 @default.
- W2904367039 cites W2800880300 @default.
- W2904367039 cites W2802579786 @default.
- W2904367039 cites W2878054156 @default.
- W2904367039 cites W4382056192 @default.
- W2904367039 doi "https://doi.org/10.3390/s18124298" @default.
- W2904367039 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6308570" @default.
- W2904367039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30563228" @default.
- W2904367039 hasPublicationYear "2018" @default.
- W2904367039 type Work @default.
- W2904367039 sameAs 2904367039 @default.
- W2904367039 citedByCount "66" @default.
- W2904367039 countsByYear W29043670392019 @default.
- W2904367039 countsByYear W29043670392020 @default.
- W2904367039 countsByYear W29043670392021 @default.
- W2904367039 countsByYear W29043670392022 @default.
- W2904367039 countsByYear W29043670392023 @default.
- W2904367039 crossrefType "journal-article" @default.
- W2904367039 hasAuthorship W2904367039A5023197214 @default.
- W2904367039 hasAuthorship W2904367039A5027737990 @default.
- W2904367039 hasAuthorship W2904367039A5029324921 @default.
- W2904367039 hasAuthorship W2904367039A5031565471 @default.
- W2904367039 hasAuthorship W2904367039A5032369315 @default.
- W2904367039 hasAuthorship W2904367039A5048155148 @default.
- W2904367039 hasAuthorship W2904367039A5052461783 @default.
- W2904367039 hasAuthorship W2904367039A5054769205 @default.
- W2904367039 hasBestOaLocation W29043670391 @default.
- W2904367039 hasConcept C128972844 @default.
- W2904367039 hasConcept C159985019 @default.
- W2904367039 hasConcept C160756335 @default.
- W2904367039 hasConcept C171250308 @default.
- W2904367039 hasConcept C192562407 @default.
- W2904367039 hasConcept C2780151546 @default.
- W2904367039 hasConcept C42067758 @default.
- W2904367039 hasConcept C43091971 @default.
- W2904367039 hasConcept C49040817 @default.
- W2904367039 hasConcept C54355233 @default.
- W2904367039 hasConcept C6260449 @default.
- W2904367039 hasConcept C86803240 @default.
- W2904367039 hasConceptScore W2904367039C128972844 @default.
- W2904367039 hasConceptScore W2904367039C159985019 @default.