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- W2904525822 abstract "Abstract Engineering/reprogramming differentiated adult somatic cells to gain the ability to differentiate into any type of cell lineage are called as induced pluripotent stem cells (iPSCs). Offering unlimited self‐renewal and differentiation potential, these iPSC are aspired to meet the growing demands in the field of regenerative medicine, tissue engineering, disease modeling, nanotechnology, and drug discovery. Biomaterial fabrication with the rapid evolution of technology increased their versatility and utility in regenerative medicine and tissue engineering, revolutionizing the stem cell biology research with the property to guide the process of proliferation, differentiation, and morphogenesis. Combining traditional culture platforms of iPSC with biomaterials aids to overcome the limitations associated with derivation, proliferation, and maturation, thereby could improve the clinical translation of iPSC. The present review discusses in brief about the reprogramming techniques for the derivation iPSC and details on several biomaterial guided differentiation of iPSC to different cell types with specific relevance to tissue engineering/regenerative medicine." @default.
- W2904525822 created "2018-12-22" @default.
- W2904525822 creator A5014492031 @default.
- W2904525822 creator A5043459440 @default.
- W2904525822 creator A5066663819 @default.
- W2904525822 creator A5069518405 @default.
- W2904525822 creator A5078709858 @default.
- W2904525822 date "2018-11-22" @default.
- W2904525822 modified "2023-09-26" @default.
- W2904525822 title "Biomaterial aided differentiation and maturation of induced pluripotent stem cells" @default.
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