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- W2904548749 abstract "Objective: This study evaluated the hypothesis that methylphenidate immediate release (MPH-IR) treatment would improve Default Mode Network (DMN) within-connectivity. Method: Resting-state functional connectivity of the main nodes of DMN was evaluated in a highly homogeneous sample of 18 drug-naive male adult participants with ADHD. Results: Comparing resting-state functional connectivity functional magnetic resonance imaging (R-fMRI) scans before and after MPH treatment focusing exclusively on within-DMN connectivity, we evidenced the strengthening of functional connectivity between two nodes of the DMN: posterior cingulate cortex (PCC) and left lateral parietal cortex (LLP). Conclusion: Our results contribute to the further understanding on how MPH affects functional connectivity within DMN of male adults with ADHD and corroborate the hypothesis of ADHD being a delayed neurodevelopmental disorder." @default.
- W2904548749 created "2018-12-22" @default.
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- W2904548749 date "2018-12-10" @default.
- W2904548749 modified "2023-10-17" @default.
- W2904548749 title "Methylphenidate Alters Functional Connectivity of Default Mode Network in Drug-Naive Male Adults With ADHD" @default.
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- W2904548749 doi "https://doi.org/10.1177/1087054718816822" @default.
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