Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904601467> ?p ?o ?g. }
- W2904601467 endingPage "297" @default.
- W2904601467 startingPage "287" @default.
- W2904601467 abstract "Mercury (Hg) is among the most deleterious contaminant in the aquatic environment and presents a serious risk to humans and ecosystems. This study evaluated the effects of Hg on oxidative stress biomarkers, DNA integrity and histological structure of the respiratory tree of Holothuria forskali exposed to different concentrations of mercury chloride HgCl2 (0.04, 0.08 and 0.16 mg L−1) for 96 h. Exposure of H. forskali to Hg led to oxidative stress with an increase in Malondialdehyde (MDA), hydrogen peroxide (H2O2), advanced oxidation protein product (AOPP) and protein carbonyls (PCO) levels in the treated groups. Alteration of the antioxidant system was also confirmed by the significant increase in glutathione (GSH), nonprotein thiol (NPSH) and vitamin C contents. Moreover, the enzymatic activity of superoxide dismutase (SOD), Glutathione peroxidase (GPX) and Catalase (CAT) increased significantly. Our research revealed that total Metallothionein (MTs) content enhanced in a dose-dependent manner. Interestingly, the exposure to this metal provoked a decrease in Acetylcholinesterase (AChE) activity. Hg genotoxicity was further evidenced by a random DNA degradation that was observed in the treated groups. The histopathological findings confirmed the biochemical results. Overall, our results indicated that mercury-induced genotoxicity, oxidative damage and histopathological injuries in the respiratory tree of H. forskali." @default.
- W2904601467 created "2018-12-22" @default.
- W2904601467 creator A5003641030 @default.
- W2904601467 creator A5041446431 @default.
- W2904601467 creator A5044779992 @default.
- W2904601467 creator A5055196566 @default.
- W2904601467 creator A5057286307 @default.
- W2904601467 creator A5062994202 @default.
- W2904601467 creator A5077475437 @default.
- W2904601467 creator A5089846400 @default.
- W2904601467 date "2018-12-17" @default.
- W2904601467 modified "2023-10-11" @default.
- W2904601467 title "Mercury disrupts redox status, up-regulates metallothionein and induces genotoxicity in respiratory tree of sea cucumber (<i>Holothuria forskali</i>)" @default.
- W2904601467 cites W1430096332 @default.
- W2904601467 cites W1538399032 @default.
- W2904601467 cites W1542073238 @default.
- W2904601467 cites W1543534715 @default.
- W2904601467 cites W1546592314 @default.
- W2904601467 cites W1549809654 @default.
- W2904601467 cites W1584313779 @default.
- W2904601467 cites W1775749144 @default.
- W2904601467 cites W183120241 @default.
- W2904601467 cites W191793640 @default.
- W2904601467 cites W1924106145 @default.
- W2904601467 cites W1964732373 @default.
- W2904601467 cites W1966684370 @default.
- W2904601467 cites W1971048984 @default.
- W2904601467 cites W1973708266 @default.
- W2904601467 cites W1973808664 @default.
- W2904601467 cites W1975893581 @default.
- W2904601467 cites W1977930150 @default.
- W2904601467 cites W1978214583 @default.
- W2904601467 cites W1978305984 @default.
- W2904601467 cites W1978353772 @default.
- W2904601467 cites W1996892966 @default.
- W2904601467 cites W2002922627 @default.
- W2904601467 cites W2005214801 @default.
- W2904601467 cites W2006370393 @default.
- W2904601467 cites W2007121764 @default.
- W2904601467 cites W2014025378 @default.
- W2904601467 cites W2016555442 @default.
- W2904601467 cites W2016978495 @default.
- W2904601467 cites W2023280604 @default.
- W2904601467 cites W2033286817 @default.
- W2904601467 cites W2039483745 @default.
- W2904601467 cites W2039708123 @default.
- W2904601467 cites W2041717515 @default.
- W2904601467 cites W2053813665 @default.
- W2904601467 cites W2055021768 @default.
- W2904601467 cites W2055708764 @default.
- W2904601467 cites W2061112376 @default.
- W2904601467 cites W2073092594 @default.
- W2904601467 cites W2074644445 @default.
- W2904601467 cites W2074926636 @default.
- W2904601467 cites W2075061874 @default.
- W2904601467 cites W2075214517 @default.
- W2904601467 cites W2075874295 @default.
- W2904601467 cites W2089347325 @default.
- W2904601467 cites W2091362651 @default.
- W2904601467 cites W2091845883 @default.
- W2904601467 cites W2097491785 @default.
- W2904601467 cites W2101422765 @default.
- W2904601467 cites W2113724451 @default.
- W2904601467 cites W2131398096 @default.
- W2904601467 cites W2142544985 @default.
- W2904601467 cites W2146711598 @default.
- W2904601467 cites W2149111395 @default.
- W2904601467 cites W2149777509 @default.
- W2904601467 cites W2163649818 @default.
- W2904601467 cites W2163970776 @default.
- W2904601467 cites W2166258948 @default.
- W2904601467 cites W2278215921 @default.
- W2904601467 cites W2292095925 @default.
- W2904601467 cites W2301388271 @default.
- W2904601467 cites W2312605682 @default.
- W2904601467 cites W2318143842 @default.
- W2904601467 cites W2495835940 @default.
- W2904601467 cites W2615008686 @default.
- W2904601467 cites W2727311176 @default.
- W2904601467 cites W776856809 @default.
- W2904601467 doi "https://doi.org/10.1080/01480545.2018.1524475" @default.
- W2904601467 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30554537" @default.
- W2904601467 hasPublicationYear "2018" @default.
- W2904601467 type Work @default.
- W2904601467 sameAs 2904601467 @default.
- W2904601467 citedByCount "12" @default.
- W2904601467 countsByYear W29046014672020 @default.
- W2904601467 countsByYear W29046014672021 @default.
- W2904601467 countsByYear W29046014672022 @default.
- W2904601467 countsByYear W29046014672023 @default.
- W2904601467 crossrefType "journal-article" @default.
- W2904601467 hasAuthorship W2904601467A5003641030 @default.
- W2904601467 hasAuthorship W2904601467A5041446431 @default.
- W2904601467 hasAuthorship W2904601467A5044779992 @default.
- W2904601467 hasAuthorship W2904601467A5055196566 @default.
- W2904601467 hasAuthorship W2904601467A5057286307 @default.
- W2904601467 hasAuthorship W2904601467A5062994202 @default.
- W2904601467 hasAuthorship W2904601467A5077475437 @default.