FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904603655> ?p ?o ?g. }

• W2904603655 endingPage "e0006984" @default.
• W2904603655 startingPage "e0006984" @default.
• W2904603655 abstract "Human rabies is an encephalitic disease transmitted by animals infected with lyssaviruses. The most common lyssavirus that causes human infection is rabies virus (RABV), the prototypic member of the genus. The incubation period of RABV in humans varies from few weeks to several months in some instances. During this prodromal period, neither antibodies nor virus is detected. Antibodies, antigen and nucleic acids are detectable only after the onset of encephalitic symptoms, at which point the outcome of the disease is nearly 100% fatal. Hence, the primary intervention for human RABV exposure and subsequent post-exposure prophylaxis relies on testing animals suspected of having rabies. The most widely used diagnostic tests in animals focus on antigen detection, RABV-encoded nucleoprotein (N protein) in brain tissues. N protein accumulates in the cytoplasm of infected cells as large and granular inclusions, which are visualized in infected brain tissues by immuno-microscopy using anti-N protein antibodies. In this study, we explored a mass spectrometry (MS) based method for N protein detection without the need for any specific antibody reagents or microscopy. The MS-based method described here is unbiased, label-free, requires no amplification and determines any previously sequenced N protein available in the database. The results demonstrate the ability of MS/MS based method for N protein detection and amino acid sequence determination in animal diagnostic samples to obtain RABV variant information. This study demonstrates a potential for future developments of rabies diagnostic tests based on MS platforms." @default.
• W2904603655 created "2018-12-22" @default.
• W2904603655 creator A5009257635 @default.
• W2904603655 creator A5025201501 @default.
• W2904603655 creator A5037347943 @default.
• W2904603655 creator A5043715737 @default.
• W2904603655 creator A5051985158 @default.
• W2904603655 creator A5055870348 @default.
• W2904603655 creator A5065624311 @default.
• W2904603655 creator A5070565858 @default.
• W2904603655 creator A5087520439 @default.
• W2904603655 creator A5090013217 @default.
• W2904603655 date "2018-12-14" @default.
• W2904603655 modified "2023-09-25" @default.
• W2904603655 title "Novel mass spectrometry based detection and identification of variants of rabies virus nucleoprotein in infected brain tissues" @default.
• W2904603655 cites W1266935 @default.
• W2904603655 cites W1577033146 @default.
• W2904603655 cites W1902007201 @default.
• W2904603655 cites W1979106169 @default.
• W2904603655 cites W2026622221 @default.
• W2904603655 cites W2045321229 @default.
• W2904603655 cites W2066447146 @default.
• W2904603655 cites W2086567928 @default.
• W2904603655 cites W2087310128 @default.
• W2904603655 cites W2104094331 @default.
• W2904603655 cites W2104227253 @default.
• W2904603655 cites W2115445096 @default.
• W2904603655 cites W2138943436 @default.
• W2904603655 cites W2167221525 @default.
• W2904603655 cites W2173312558 @default.
• W2904603655 cites W2317681338 @default.
• W2904603655 cites W2470821155 @default.
• W2904603655 cites W2488048472 @default.
• W2904603655 cites W2528616122 @default.
• W2904603655 cites W2579593334 @default.
• W2904603655 cites W2736913410 @default.
• W2904603655 cites W2759363431 @default.
• W2904603655 cites W3021677759 @default.
• W2904603655 cites W332231204 @default.
• W2904603655 cites W67199098 @default.
• W2904603655 doi "https://doi.org/10.1371/journal.pntd.0006984" @default.
• W2904603655 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6310296" @default.
• W2904603655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30550539" @default.
• W2904603655 hasPublicationYear "2018" @default.
• W2904603655 type Work @default.
• W2904603655 sameAs 2904603655 @default.
• W2904603655 citedByCount "2" @default.
• W2904603655 countsByYear W29046036552019 @default.
• W2904603655 countsByYear W29046036552021 @default.
• W2904603655 crossrefType "journal-article" @default.
• W2904603655 hasAuthorship W2904603655A5009257635 @default.
• W2904603655 hasAuthorship W2904603655A5025201501 @default.
• W2904603655 hasAuthorship W2904603655A5037347943 @default.
• W2904603655 hasAuthorship W2904603655A5043715737 @default.
• W2904603655 hasAuthorship W2904603655A5051985158 @default.
• W2904603655 hasAuthorship W2904603655A5055870348 @default.
• W2904603655 hasAuthorship W2904603655A5065624311 @default.
• W2904603655 hasAuthorship W2904603655A5070565858 @default.
• W2904603655 hasAuthorship W2904603655A5087520439 @default.
• W2904603655 hasAuthorship W2904603655A5090013217 @default.
• W2904603655 hasBestOaLocation W29046036551 @default.
• W2904603655 hasConcept C159047783 @default.
• W2904603655 hasConcept C159654299 @default.
• W2904603655 hasConcept C203014093 @default.
• W2904603655 hasConcept C2522874641 @default.
• W2904603655 hasConcept C2776849203 @default.
• W2904603655 hasConcept C2777961786 @default.
• W2904603655 hasConcept C2777974785 @default.
• W2904603655 hasConcept C2779811178 @default.
• W2904603655 hasConcept C60325843 @default.
• W2904603655 hasConcept C86803240 @default.
• W2904603655 hasConceptScore W2904603655C159047783 @default.
• W2904603655 hasConceptScore W2904603655C159654299 @default.
• W2904603655 hasConceptScore W2904603655C203014093 @default.
• W2904603655 hasConceptScore W2904603655C2522874641 @default.
• W2904603655 hasConceptScore W2904603655C2776849203 @default.
• W2904603655 hasConceptScore W2904603655C2777961786 @default.
• W2904603655 hasConceptScore W2904603655C2777974785 @default.
• W2904603655 hasConceptScore W2904603655C2779811178 @default.
• W2904603655 hasConceptScore W2904603655C60325843 @default.
• W2904603655 hasConceptScore W2904603655C86803240 @default.
• W2904603655 hasIssue "12" @default.
• W2904603655 hasLocation W29046036551 @default.
• W2904603655 hasLocation W29046036552 @default.
• W2904603655 hasLocation W29046036553 @default.
• W2904603655 hasLocation W29046036554 @default.
• W2904603655 hasLocation W29046036555 @default.
• W2904603655 hasOpenAccess W2904603655 @default.
• W2904603655 hasPrimaryLocation W29046036551 @default.
• W2904603655 hasRelatedWork W1506799144 @default.
• W2904603655 hasRelatedWork W1609743444 @default.
• W2904603655 hasRelatedWork W1977371468 @default.
• W2904603655 hasRelatedWork W2007280898 @default.
• W2904603655 hasRelatedWork W2062652575 @default.
• W2904603655 hasRelatedWork W2071047793 @default.
• W2904603655 hasRelatedWork W2072867016 @default.
• W2904603655 hasRelatedWork W2097299061 @default.
• W2904603655 hasRelatedWork W2401800135 @default.

• next