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- W2904616103 abstract "The rapid developments of gene therapy are benefit from the construction of efficient gene vectors, which help therapy genes efficiently overcome the barriers in the transport and transfection. Condensing DNA into nanoparticles is a crucial role in gene transfection, and the electrostatic interactions of synthetic cationic liposomes and cationic polymers with DNA are generally used for condensing DNA. Recent research has shown that the introduction of the hydrophobic interaction, hydrogen bonding, and coordinative interactions to the gene delivery vectors is also very important for DNA condensation, delivery, and transfection. This review focuses on the four types of interactions in condensed DNA nanoparticles, which could provide a new perspective for improving gene transfection efficacy." @default.
- W2904616103 created "2018-12-22" @default.
- W2904616103 creator A5000644083 @default.
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- W2904616103 creator A5032985347 @default.
- W2904616103 creator A5038339911 @default.
- W2904616103 creator A5054633586 @default.
- W2904616103 date "2018-12-13" @default.
- W2904616103 modified "2023-10-12" @default.
- W2904616103 title "Interactions in DNA Condensation: An Important Factor for Improving the Efficacy of Gene Transfection" @default.
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