Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904643181> ?p ?o ?g. }
- W2904643181 endingPage "1083" @default.
- W2904643181 startingPage "1074" @default.
- W2904643181 abstract "An asymmetric intermolecular, three-component radical-initiated dicarbofunctionalization of 1,1-diarylalkenes with diverse carbon-centered radical precursors and electron-rich heteroaromatics by a copper(I) and chiral phosphoric acid cooperative catalysis strategy has been developed, providing straightforward access to chiral triarylmethanes bearing quaternary all-carbon stereocenters with high efficiency as well as excellent chemo- and enantioselectivity. The key to success is not only the introduction of a sterically demanding chiral phosphoric acid to favor radical difunctionalization over the otherwise remarkable side reactions but also the in situ generation of carbocation intermediates from benzylic radical to realize asymmetric induction with the aid of a removable hydroxy directing group via cooperative interactions with chiral phosphate. Density functional theory calculations elucidated the critical chiral environment created by the hydrogen-bonding and ion-pair interactions between the chiral phosphoric acid catalyst and substrates, which leads to the enantioselective C-C bond formation." @default.
- W2904643181 created "2018-12-22" @default.
- W2904643181 creator A5008291744 @default.
- W2904643181 creator A5009790777 @default.
- W2904643181 creator A5015073580 @default.
- W2904643181 creator A5034676224 @default.
- W2904643181 creator A5035674649 @default.
- W2904643181 creator A5069429673 @default.
- W2904643181 creator A5070331807 @default.
- W2904643181 creator A5088566937 @default.
- W2904643181 creator A5088854097 @default.
- W2904643181 date "2018-12-18" @default.
- W2904643181 modified "2023-10-17" @default.
- W2904643181 title "Cu/Chiral Phosphoric Acid-Catalyzed Asymmetric Three-Component Radical-Initiated 1,2-Dicarbofunctionalization of Alkenes" @default.
- W2904643181 cites W1834088233 @default.
- W2904643181 cites W1966912785 @default.
- W2904643181 cites W1979890076 @default.
- W2904643181 cites W1980896239 @default.
- W2904643181 cites W1981192266 @default.
- W2904643181 cites W1983271503 @default.
- W2904643181 cites W1984801377 @default.
- W2904643181 cites W1994517024 @default.
- W2904643181 cites W1994685053 @default.
- W2904643181 cites W1995724100 @default.
- W2904643181 cites W1996681043 @default.
- W2904643181 cites W1998216903 @default.
- W2904643181 cites W1998740595 @default.
- W2904643181 cites W2001086298 @default.
- W2904643181 cites W2003406192 @default.
- W2904643181 cites W2004174458 @default.
- W2904643181 cites W2004256449 @default.
- W2904643181 cites W2009008810 @default.
- W2904643181 cites W2010662941 @default.
- W2904643181 cites W2011009404 @default.
- W2904643181 cites W2014365220 @default.
- W2904643181 cites W2019442835 @default.
- W2904643181 cites W2020931253 @default.
- W2904643181 cites W2033512764 @default.
- W2904643181 cites W2042336219 @default.
- W2904643181 cites W2044854137 @default.
- W2904643181 cites W2049928757 @default.
- W2904643181 cites W2051441149 @default.
- W2904643181 cites W2053941042 @default.
- W2904643181 cites W2059883306 @default.
- W2904643181 cites W2064815026 @default.
- W2904643181 cites W2067151318 @default.
- W2904643181 cites W2069702158 @default.
- W2904643181 cites W2072591300 @default.
- W2904643181 cites W2074960707 @default.
- W2904643181 cites W2077621718 @default.
- W2904643181 cites W2077895811 @default.
- W2904643181 cites W2079821320 @default.
- W2904643181 cites W2084848421 @default.
- W2904643181 cites W2085351645 @default.
- W2904643181 cites W2085495486 @default.
- W2904643181 cites W2086373875 @default.
- W2904643181 cites W2089101147 @default.
- W2904643181 cites W2095958188 @default.
- W2904643181 cites W2097520612 @default.
- W2904643181 cites W2105492427 @default.
- W2904643181 cites W2113610830 @default.
- W2904643181 cites W2114745719 @default.
- W2904643181 cites W2118422638 @default.
- W2904643181 cites W2121528866 @default.
- W2904643181 cites W2128711500 @default.
- W2904643181 cites W2158974750 @default.
- W2904643181 cites W2161235007 @default.
- W2904643181 cites W2171850634 @default.
- W2904643181 cites W2173809998 @default.
- W2904643181 cites W2188186545 @default.
- W2904643181 cites W2278002274 @default.
- W2904643181 cites W2293509006 @default.
- W2904643181 cites W2312964059 @default.
- W2904643181 cites W2314846974 @default.
- W2904643181 cites W2318202219 @default.
- W2904643181 cites W2318384131 @default.
- W2904643181 cites W2318461157 @default.
- W2904643181 cites W2319137370 @default.
- W2904643181 cites W2319534265 @default.
- W2904643181 cites W2319831200 @default.
- W2904643181 cites W2324572467 @default.
- W2904643181 cites W2331533611 @default.
- W2904643181 cites W2334110708 @default.
- W2904643181 cites W2334721406 @default.
- W2904643181 cites W2335400562 @default.
- W2904643181 cites W2335533341 @default.
- W2904643181 cites W2336805901 @default.
- W2904643181 cites W2398350748 @default.
- W2904643181 cites W2467179714 @default.
- W2904643181 cites W2473622289 @default.
- W2904643181 cites W2515068481 @default.
- W2904643181 cites W2517539729 @default.
- W2904643181 cites W2519805142 @default.
- W2904643181 cites W2520539854 @default.
- W2904643181 cites W2520813356 @default.
- W2904643181 cites W2531917873 @default.
- W2904643181 cites W2551877008 @default.
- W2904643181 cites W2552416281 @default.