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- W2904651143 abstract "The aim of our study was to investigate the cases of drug-induced acute pancreatitis (DIAP) with hypertriglyceridemia as the mechanism of injury.A MEDLINE search (1963-2018) of the English language literature was performed looking for all human case reports of adults (>18 years old) with hypertriglyceridemia as the mechanism of DIAP. The latest search date was February 28, 2018. Drugs were classified into probability groups based on a classification used by Badalov et al (Clin Gastroenterol Hepatol. 2007;5:648-661).The search revealed a total of 76 cases in 59 published reports. A total of 25 medications were found to be implicated in DIAP secondary to hypertriglyceridemia mechanism. Most of acute pancreatitis cases were mild or moderately severe with favorable outcomes. In 3 cases involving tamoxifen, pagaspargase, and quetiapine, patient death was the outcome. Plasmapheresis was only used in 9 cases in an effort to decrease triglyceride levels.Hypertriglyceridemia-associated DIAP is a rare phenomenon, and the current systematic review provides a summary of drugs that have been implicated in this phenomenon, which allow physicians to be oriented about this adverse effect when these drugs are used." @default.
- W2904651143 created "2018-12-22" @default.
- W2904651143 creator A5026822880 @default.
- W2904651143 creator A5044437817 @default.
- W2904651143 creator A5087463344 @default.
- W2904651143 date "2019-01-01" @default.
- W2904651143 modified "2023-10-03" @default.
- W2904651143 title "Hypertriglyceridemia-Associated Drug-Induced Acute Pancreatitis" @default.
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- W2904651143 doi "https://doi.org/10.1097/mpa.0000000000001190" @default.
- W2904651143 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30531242" @default.
- W2904651143 hasPublicationYear "2019" @default.
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