FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904669002> ?p ?o ?g. }

• W2904669002 endingPage "90" @default.
• W2904669002 startingPage "84" @default.
• W2904669002 abstract "While the association between platelet activation and hepatic fibrosis has been previously demonstrated in animal studies; the utility of anti-platelet agents in reversing the progression of hepatic fibrosis requires further review. Utilizing systematic review methods, we provide to our knowledge the first meta-analysis combining evidence from all studies aimed to establish the effect of anti-platelet agents in the prevention of hepatic fibrosis. We searched Medline, EMBASE and PubMed databases from inception to October 2018 to identify all studies aimed at evaluating the role of anti-platelet agents in the prevention of hepatic fibrosis. The primary outcome was hepatic fibrosis. The initial title, abstract, and full-text screening were performed in duplicate. Risk of bias was evaluated using the Newcastle–Ottawa Scale. A fixed-effect generic inverse variance method was used to create a pooled estimate of the odds of hepatic fibrosis in patients with anti-platelet agents versus without anti-platelet agents. Among the 2310 unique articles identified during the title screening, 4 studies with a combined population of 3141 patients were deemed eligible for inclusion into the meta-analysis establishing the effect of anti-platelet agents on hepatic fibrosis. One study failed to report their findings in the entire cohort, electing to instead summarize the effects of anti-platelets within subgroups categorized by fibrotic risk factors. Use of anti-platelets was associated with 32% decreased odds of hepatic fibrosis, (adjusted pooled OR 0.68; CI 0.56–0.82, p ≤ 0.0001). The statistical heterogeneity among the studies was insignificant. Use of anti-platelet agents is associated with the decreased odds of hepatic fibrosis. Due to limited evidence, future high-quality randomized controlled trials with larger comparative samples are required to further delineate the potential beneficial effects of these drugs in preventing hepatic fibrosis." @default.
• W2904669002 created "2018-12-22" @default.
• W2904669002 creator A5010230468 @default.
• W2904669002 creator A5038808879 @default.
• W2904669002 creator A5053456278 @default.
• W2904669002 creator A5060181991 @default.
• W2904669002 creator A5068997870 @default.
• W2904669002 creator A5084344492 @default.
• W2904669002 date "2018-12-12" @default.
• W2904669002 modified "2023-10-02" @default.
• W2904669002 title "Use of anti-platelet agents in the prevention of hepatic fibrosis in patients at risk for chronic liver disease: a systematic review and meta-analysis" @default.
• W2904669002 cites W2005501262 @default.
• W2904669002 cites W2016974410 @default.
• W2904669002 cites W2025780125 @default.
• W2904669002 cites W2055439705 @default.
• W2904669002 cites W2056985589 @default.
• W2904669002 cites W2062501613 @default.
• W2904669002 cites W2085123525 @default.
• W2904669002 cites W2090622665 @default.
• W2904669002 cites W2093310669 @default.
• W2904669002 cites W2106838509 @default.
• W2904669002 cites W2112244490 @default.
• W2904669002 cites W2121339421 @default.
• W2904669002 cites W2121815683 @default.
• W2904669002 cites W2125435699 @default.
• W2904669002 cites W2161980547 @default.
• W2904669002 cites W2229541017 @default.
• W2904669002 cites W2516759517 @default.
• W2904669002 cites W2623602164 @default.
• W2904669002 cites W2796313776 @default.
• W2904669002 cites W2802823850 @default.
• W2904669002 cites W2894897498 @default.
• W2904669002 doi "https://doi.org/10.1007/s12072-018-9918-2" @default.
• W2904669002 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6675411" @default.
• W2904669002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30539518" @default.
• W2904669002 hasPublicationYear "2018" @default.
• W2904669002 type Work @default.
• W2904669002 sameAs 2904669002 @default.
• W2904669002 citedByCount "21" @default.
• W2904669002 countsByYear W29046690022019 @default.
• W2904669002 countsByYear W29046690022020 @default.
• W2904669002 countsByYear W29046690022021 @default.
• W2904669002 countsByYear W29046690022022 @default.
• W2904669002 countsByYear W29046690022023 @default.
• W2904669002 crossrefType "journal-article" @default.
• W2904669002 hasAuthorship W2904669002A5010230468 @default.
• W2904669002 hasAuthorship W2904669002A5038808879 @default.
• W2904669002 hasAuthorship W2904669002A5053456278 @default.
• W2904669002 hasAuthorship W2904669002A5060181991 @default.
• W2904669002 hasAuthorship W2904669002A5068997870 @default.
• W2904669002 hasAuthorship W2904669002A5084344492 @default.
• W2904669002 hasBestOaLocation W29046690022 @default.
• W2904669002 hasConcept C126322002 @default.
• W2904669002 hasConcept C156957248 @default.
• W2904669002 hasConcept C2777214474 @default.
• W2904669002 hasConcept C2779102576 @default.
• W2904669002 hasConcept C2780559512 @default.
• W2904669002 hasConcept C2908647359 @default.
• W2904669002 hasConcept C2993667909 @default.
• W2904669002 hasConcept C41260117 @default.
• W2904669002 hasConcept C71924100 @default.
• W2904669002 hasConcept C89560881 @default.
• W2904669002 hasConcept C90924648 @default.
• W2904669002 hasConcept C95190672 @default.
• W2904669002 hasConcept C99454951 @default.
• W2904669002 hasConceptScore W2904669002C126322002 @default.
• W2904669002 hasConceptScore W2904669002C156957248 @default.
• W2904669002 hasConceptScore W2904669002C2777214474 @default.
• W2904669002 hasConceptScore W2904669002C2779102576 @default.
• W2904669002 hasConceptScore W2904669002C2780559512 @default.
• W2904669002 hasConceptScore W2904669002C2908647359 @default.
• W2904669002 hasConceptScore W2904669002C2993667909 @default.
• W2904669002 hasConceptScore W2904669002C41260117 @default.
• W2904669002 hasConceptScore W2904669002C71924100 @default.
• W2904669002 hasConceptScore W2904669002C89560881 @default.
• W2904669002 hasConceptScore W2904669002C90924648 @default.
• W2904669002 hasConceptScore W2904669002C95190672 @default.
• W2904669002 hasConceptScore W2904669002C99454951 @default.
• W2904669002 hasIssue "1" @default.
• W2904669002 hasLocation W29046690021 @default.
• W2904669002 hasLocation W29046690022 @default.
• W2904669002 hasLocation W29046690023 @default.
• W2904669002 hasLocation W29046690024 @default.
• W2904669002 hasOpenAccess W2904669002 @default.
• W2904669002 hasPrimaryLocation W29046690021 @default.
• W2904669002 hasRelatedWork W103547024 @default.
• W2904669002 hasRelatedWork W1731674693 @default.
• W2904669002 hasRelatedWork W1966263252 @default.
• W2904669002 hasRelatedWork W1980748566 @default.
• W2904669002 hasRelatedWork W1984717806 @default.
• W2904669002 hasRelatedWork W2026400761 @default.
• W2904669002 hasRelatedWork W2043383895 @default.
• W2904669002 hasRelatedWork W2104682956 @default.
• W2904669002 hasRelatedWork W2370602281 @default.
• W2904669002 hasRelatedWork W2382531208 @default.
• W2904669002 hasVolume "13" @default.
• W2904669002 isParatext "false" @default.
• W2904669002 isRetracted "false" @default.

• next