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- W2904684424 abstract "Retinoblastoma, the most common primary intraocular malignancy of the young, is a prototype hereditary cancer. Due to its fairly predictable Mendelian inheritance, easily examinable tumors, and early age of presentation, RB has served as the most extensively studied model for genetics in cancer. The genetic strides in RB have progressed at an exponential rate since the 1970s. The highly morbid, reasonably curable and distinctly predictable inheritance pattern of RB; not to mention its propensity to affect our young, forms the basis of aggressively encouraging genetic diagnosis in all patients of RB. In this article, we present the basic and clinically relevant concepts of the genetics retinoblastoma." @default.
- W2904684424 created "2018-12-22" @default.
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- W2904684424 date "2018-01-01" @default.
- W2904684424 modified "2023-09-23" @default.
- W2904684424 title "Knudson to embryo selection: A story of the genetics of retinoblastoma" @default.
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- W2904684424 doi "https://doi.org/10.4103/tjo.tjo_37_18" @default.
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