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- W2904690667 abstract "Studies have linked self-reported discrimination to telomere attrition, a biological marker of accelerated cellular aging. However, it is unknown whether intersections between social categories—race, socioeconomic status (SES), sex, and age—influence the association of varying forms of discrimination with telomere length. We examined these associations in a socioeconomically and racially/ethnically diverse urban sample. Cross-sectional data were from 341 middle-aged (30–64 years) African American and White, community participants in the Healthy Aging in Neighborhoods of Diversity across the Life Span Study (HANDLS). Multiple regression models examined up to 3-way interactions between a discrimination measure (i.e., everyday, racial, gender, lifetime burden, and frequency of discrimination across sources) and two social categories. After adjusting for depressive symptoms, waist circumference, and lifetime substance use, two themes emerged: 1) among women with higher SES, a) greater lifetime discrimination burden (b = -0.23, p = .011), gender discrimination (b = -0.29, p = .040), and racial discrimination (b = -0.24, p = 0.023) and 2) among younger adults, irrespective of race and sex, greater frequency of discrimination across sources (b = 0.002, p = .008) was associated with shorter telomeres. Irrespective of race, women with higher SES and younger adults reporting greater discrimination may be at particular risk for accelerated aging. Telomere attrition promotes and accelerates chronic health conditions for which there are health disparities. Future research explicating intersections among specific discrimination indices and social categories is warranted." @default.
- W2904690667 created "2018-12-22" @default.
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- W2904690667 date "2019-02-01" @default.
- W2904690667 modified "2023-10-14" @default.
- W2904690667 title "Interpersonal-level discrimination indices, sociodemographic factors, and telomere length in African-Americans and Whites" @default.
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- W2904690667 doi "https://doi.org/10.1016/j.biopsycho.2018.12.004" @default.
- W2904690667 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6438165" @default.
- W2904690667 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30553820" @default.
- W2904690667 hasPublicationYear "2019" @default.
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