FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904694030> ?p ?o ?g. }

• W2904694030 endingPage "1194" @default.
• W2904694030 startingPage "1188" @default.
• W2904694030 abstract "The importance of the biophysical cellular environment in cancer development has been increasingly recognised but so far has been only superficially studied. Here we investigated the effect of cell-like substrate topography on ovarian cancer cell behaviour and potential underlying signalling pathways. We observed changes in cell morphology in response to substrate topography, which implies modification of structure-function associations. Differences in focal adhesion signalling and Rho/ROCK activity suggested their involvement in the biomechanically-driven cellular responses. Cell-like topography was also shown to modulate the MAPK pathway and hence potentially regulate cell proliferation. The selective regulation of the cells by the mechanotransduction pathways that we noted has wide ranging implications for understanding cancer development. We established that the physical architecture of cell culture substrate is sufficient to influence cancer cell behaviour, independent of genetic composition or biochemical milieu." @default.
• W2904694030 created "2018-12-22" @default.
• W2904694030 creator A5007238782 @default.
• W2904694030 creator A5012364702 @default.
• W2904694030 creator A5050390201 @default.
• W2904694030 creator A5062301649 @default.
• W2904694030 creator A5069644086 @default.
• W2904694030 date "2019-01-01" @default.
• W2904694030 modified "2023-09-25" @default.
• W2904694030 title "The extracellular topographical environment influences ovarian cancer cell behaviour" @default.
• W2904694030 cites W1827954455 @default.
• W2904694030 cites W1971541515 @default.
• W2904694030 cites W1991115754 @default.
• W2904694030 cites W2012347139 @default.
• W2904694030 cites W2014280822 @default.
• W2904694030 cites W2016611881 @default.
• W2904694030 cites W2018987816 @default.
• W2904694030 cites W2023251706 @default.
• W2904694030 cites W2035802939 @default.
• W2904694030 cites W2074352273 @default.
• W2904694030 cites W2078088491 @default.
• W2904694030 cites W2100122781 @default.
• W2904694030 cites W2108828732 @default.
• W2904694030 cites W2116413963 @default.
• W2904694030 cites W2142893849 @default.
• W2904694030 cites W2144421573 @default.
• W2904694030 cites W2154421213 @default.
• W2904694030 cites W2176509929 @default.
• W2904694030 cites W2263006505 @default.
• W2904694030 cites W2283883330 @default.
• W2904694030 cites W2316426285 @default.
• W2904694030 cites W2588029840 @default.
• W2904694030 cites W2588726331 @default.
• W2904694030 cites W2614146260 @default.
• W2904694030 doi "https://doi.org/10.1016/j.bbrc.2018.12.067" @default.
• W2904694030 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30558791" @default.
• W2904694030 hasPublicationYear "2019" @default.
• W2904694030 type Work @default.
• W2904694030 sameAs 2904694030 @default.
• W2904694030 citedByCount "5" @default.
• W2904694030 countsByYear W29046940302020 @default.
• W2904694030 countsByYear W29046940302021 @default.
• W2904694030 countsByYear W29046940302022 @default.
• W2904694030 countsByYear W29046940302023 @default.
• W2904694030 crossrefType "journal-article" @default.
• W2904694030 hasAuthorship W2904694030A5007238782 @default.
• W2904694030 hasAuthorship W2904694030A5012364702 @default.
• W2904694030 hasAuthorship W2904694030A5050390201 @default.
• W2904694030 hasAuthorship W2904694030A5062301649 @default.
• W2904694030 hasAuthorship W2904694030A5069644086 @default.
• W2904694030 hasConcept C121608353 @default.
• W2904694030 hasConcept C1491633281 @default.
• W2904694030 hasConcept C150555746 @default.
• W2904694030 hasConcept C151166631 @default.
• W2904694030 hasConcept C181104049 @default.
• W2904694030 hasConcept C2780427987 @default.
• W2904694030 hasConcept C28406088 @default.
• W2904694030 hasConcept C3018449070 @default.
• W2904694030 hasConcept C54355233 @default.
• W2904694030 hasConcept C62112901 @default.
• W2904694030 hasConcept C62478195 @default.
• W2904694030 hasConcept C85789140 @default.
• W2904694030 hasConcept C86803240 @default.
• W2904694030 hasConcept C95444343 @default.
• W2904694030 hasConcept C96232424 @default.
• W2904694030 hasConceptScore W2904694030C121608353 @default.
• W2904694030 hasConceptScore W2904694030C1491633281 @default.
• W2904694030 hasConceptScore W2904694030C150555746 @default.
• W2904694030 hasConceptScore W2904694030C151166631 @default.
• W2904694030 hasConceptScore W2904694030C181104049 @default.
• W2904694030 hasConceptScore W2904694030C2780427987 @default.
• W2904694030 hasConceptScore W2904694030C28406088 @default.
• W2904694030 hasConceptScore W2904694030C3018449070 @default.
• W2904694030 hasConceptScore W2904694030C54355233 @default.
• W2904694030 hasConceptScore W2904694030C62112901 @default.
• W2904694030 hasConceptScore W2904694030C62478195 @default.
• W2904694030 hasConceptScore W2904694030C85789140 @default.
• W2904694030 hasConceptScore W2904694030C86803240 @default.
• W2904694030 hasConceptScore W2904694030C95444343 @default.
• W2904694030 hasConceptScore W2904694030C96232424 @default.
• W2904694030 hasIssue "4" @default.
• W2904694030 hasLocation W29046940301 @default.
• W2904694030 hasLocation W29046940302 @default.
• W2904694030 hasOpenAccess W2904694030 @default.
• W2904694030 hasPrimaryLocation W29046940301 @default.
• W2904694030 hasRelatedWork W192658524 @default.
• W2904694030 hasRelatedWork W1998016140 @default.
• W2904694030 hasRelatedWork W2011227811 @default.
• W2904694030 hasRelatedWork W2038964728 @default.
• W2904694030 hasRelatedWork W2100773611 @default.
• W2904694030 hasRelatedWork W2131627130 @default.
• W2904694030 hasRelatedWork W2171065062 @default.
• W2904694030 hasRelatedWork W2552180582 @default.
• W2904694030 hasRelatedWork W2774104907 @default.
• W2904694030 hasRelatedWork W2904694030 @default.
• W2904694030 hasVolume "508" @default.
• W2904694030 isParatext "false" @default.
• W2904694030 isRetracted "false" @default.

• next