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- W2904719774 abstract "Background:HepatitisCisamajorcauseofliver-relatedmorbidityandmortalityandrepresentsa majorpublichealthprobleminEgyptandworldwide.Thereisgrowingevidenceasregardtothe associationbetweenhepatitisCvirus(HCV)infectionandtype2diabetesmellitus.However,the mutuallinkandrelatedvirologicalimplicationhavenotbeenfullyclarified.Insulinresistance(IR) playsaprimaryroleinthedevelopmentoftype2DM.Thisissupportedbytheresultsofprospective longitudinalstudiesshowingthatIRisthebestpredictorofthedevelopmentoftype2DM,preceding itsonsetby10-20years. Aim:ToassessthecorrelationbetweenHCVmorbidityandInsulinresistance(IR)detectedby HOMAtestinnonediabeticnoneobeseHCVpatients Materials&Method:Thestudyparticipantsweresubcategorizedintotwogroups,Group(I): included867healthysubjects(negativeHCVRNA)asacontrolgroup.Group(II):included277 patientswithchronicHCVasastudygroup.The2groupsweresubjectedtothoroughhistorytaking, fullclinicalexamination,Anthropometricstudy,ultrasonographicexaminationandlaboratory investigationsincludingliverfunctions,viralmarkers,andqualitativePCRforHCVRNA,lipid profile,glucoseprofileandHOMAtest. Results:ThisstudyrevealedhigherinsulinresistanceintheHCVstudygroupthanthecontrolgroup." @default.
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- W2904719774 date "2010-10-01" @default.
- W2904719774 modified "2023-09-26" @default.
- W2904719774 title "Relationship between HCV infection and Insulin resistance in non-obese non- diabetic patients" @default.
- W2904719774 doi "https://doi.org/10.12816/ejhm.2010.16953" @default.
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