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- W2904804931 abstract "Abstract We identified neurons in dorsal premotor cortex (PMd) of the macaque brain that respond during execution and observation of reaching-to-grasp actions, thus fulfilling the mirror neuron (MirN) criterion. During observation, the percentage of grip-selective MirNs in PMd and area F5 were comparable, and the selectivity indices in the two areas were similar. During execution, F5-MirNs were more selective than PMd–MirNs for grip, which was reflected in the higher selectivity indices in F5 than in PMd. PMd displayed grip-related information earlier than F5 during both conditions. In both areas, the number of neurons exhibiting congruent visual and motor selectivity did not differ from that expected by chance. However, both the PMd and F5 neuronal ensembles provided observation–execution matching, suggesting that the congruency may be achieved in a distributed fashion across the selective elements of the population. Furthermore, representational similarity analysis revealed that grip encoding in PMd and F5 is alike during both observation and execution. Our study provides direct evidence of mirror activity in PMd during observation of forelimb movements, and suggests that PMd is a node of the MirN circuit." @default.
- W2904804931 created "2018-12-22" @default.
- W2904804931 creator A5019655347 @default.
- W2904804931 creator A5055313909 @default.
- W2904804931 date "2018-12-07" @default.
- W2904804931 modified "2023-10-01" @default.
- W2904804931 title "Neurons in the Macaque Dorsal Premotor Cortex Respond to Execution and Observation of Actions" @default.
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- W2904804931 doi "https://doi.org/10.1093/cercor/bhy304" @default.
- W2904804931 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30535385" @default.
- W2904804931 hasPublicationYear "2018" @default.
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