Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904922221> ?p ?o ?g. }
- W2904922221 endingPage "17" @default.
- W2904922221 startingPage "8" @default.
- W2904922221 abstract "Today, detailed risk assessment can only be performed for a few percent of the total number of current-use chemicals because of lack of data. Toxicity data is, therefore, needed for a substantial number of untested chemicals, a task that requires improved and faster chemical risk assessment strategies that are cost-efficient, human relevant and ethically responsible. In this commentary, we use a case study on five known thyroid toxic chemicals (perfluorooctanesulfonic acid, triclosan, tetrabromobisphenol A, decabromodiphenyl ether and hexabromocyclododecane) to explore the use of in vitro data for hazard assessment together with human biomonitoring (HBM) data for exposure assessment when evaluating human risk. Based on the case study, we conclude that in vitro and HBM data can be used for risk ranking of chemicals. We envision that an in vitro/HBM approach can use data from studies such as the big European initiative Human Biomonitoring for Europe (HBM4EU) together with human-relevant in vitro data to make alternative risk assessment more valuable to finally be able to ‘stand-alone’." @default.
- W2904922221 created "2018-12-22" @default.
- W2904922221 creator A5013486358 @default.
- W2904922221 creator A5035402314 @default.
- W2904922221 creator A5054894074 @default.
- W2904922221 creator A5055343723 @default.
- W2904922221 creator A5056610455 @default.
- W2904922221 date "2019-06-01" @default.
- W2904922221 modified "2023-09-27" @default.
- W2904922221 title "Chemical risk assessment based on in vitro and human biomonitoring data: A case study on thyroid toxicants" @default.
- W2904922221 cites W1056159955 @default.
- W2904922221 cites W1579194856 @default.
- W2904922221 cites W1618516170 @default.
- W2904922221 cites W1879339955 @default.
- W2904922221 cites W1963702577 @default.
- W2904922221 cites W1966283710 @default.
- W2904922221 cites W1970449952 @default.
- W2904922221 cites W1972238619 @default.
- W2904922221 cites W1975926327 @default.
- W2904922221 cites W1975942932 @default.
- W2904922221 cites W1977970202 @default.
- W2904922221 cites W1979969340 @default.
- W2904922221 cites W1981265529 @default.
- W2904922221 cites W1981425539 @default.
- W2904922221 cites W1988121716 @default.
- W2904922221 cites W1988298680 @default.
- W2904922221 cites W1991561031 @default.
- W2904922221 cites W1992470121 @default.
- W2904922221 cites W1994393818 @default.
- W2904922221 cites W1994746691 @default.
- W2904922221 cites W1997621764 @default.
- W2904922221 cites W2005063716 @default.
- W2904922221 cites W2011618923 @default.
- W2904922221 cites W2012133139 @default.
- W2904922221 cites W2012557215 @default.
- W2904922221 cites W2017399463 @default.
- W2904922221 cites W2022772992 @default.
- W2904922221 cites W2023620420 @default.
- W2904922221 cites W2024598483 @default.
- W2904922221 cites W2025317724 @default.
- W2904922221 cites W2028401108 @default.
- W2904922221 cites W2030254991 @default.
- W2904922221 cites W2032469875 @default.
- W2904922221 cites W2033115653 @default.
- W2904922221 cites W2034108896 @default.
- W2904922221 cites W2034510663 @default.
- W2904922221 cites W2041680723 @default.
- W2904922221 cites W2043207983 @default.
- W2904922221 cites W2045753556 @default.
- W2904922221 cites W2046134651 @default.
- W2904922221 cites W2054590302 @default.
- W2904922221 cites W2056529046 @default.
- W2904922221 cites W2058922852 @default.
- W2904922221 cites W2062585450 @default.
- W2904922221 cites W2062753439 @default.
- W2904922221 cites W2062868725 @default.
- W2904922221 cites W2063319145 @default.
- W2904922221 cites W2064990262 @default.
- W2904922221 cites W2065445500 @default.
- W2904922221 cites W2066529159 @default.
- W2904922221 cites W2069108174 @default.
- W2904922221 cites W2076100364 @default.
- W2904922221 cites W2077095632 @default.
- W2904922221 cites W2082587707 @default.
- W2904922221 cites W2082614021 @default.
- W2904922221 cites W2082802165 @default.
- W2904922221 cites W2082866970 @default.
- W2904922221 cites W2089657874 @default.
- W2904922221 cites W2104209550 @default.
- W2904922221 cites W2111422484 @default.
- W2904922221 cites W2119259626 @default.
- W2904922221 cites W2119446591 @default.
- W2904922221 cites W2121516119 @default.
- W2904922221 cites W2121965166 @default.
- W2904922221 cites W2124241458 @default.
- W2904922221 cites W2128676243 @default.
- W2904922221 cites W2129225932 @default.
- W2904922221 cites W2132024398 @default.
- W2904922221 cites W2134652150 @default.
- W2904922221 cites W2138527723 @default.
- W2904922221 cites W2140858853 @default.
- W2904922221 cites W2141254815 @default.
- W2904922221 cites W2141387024 @default.
- W2904922221 cites W2144245956 @default.
- W2904922221 cites W2144281413 @default.
- W2904922221 cites W2147334256 @default.
- W2904922221 cites W2152739011 @default.
- W2904922221 cites W2157660552 @default.
- W2904922221 cites W2178275564 @default.
- W2904922221 cites W2217805693 @default.
- W2904922221 cites W2290279553 @default.
- W2904922221 cites W2293271133 @default.
- W2904922221 cites W2307022262 @default.
- W2904922221 cites W2327443057 @default.
- W2904922221 cites W2417388610 @default.
- W2904922221 cites W2508238495 @default.
- W2904922221 cites W2512508208 @default.
- W2904922221 cites W2530391704 @default.