Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904926213> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2904926213 abstract "Colorectal cancer (CRC) is one of the most common cancers worldwide. CRC develops from precancerous polyps in the colon or rectum and is preventable by an early diagnosis and with the removal of precursor lesions. Numerous genetics and epigenetic alterations transform benign polyps to malignant tumors by affecting different pathways. Over the past decade, increasing evidence represent the utility of cell-free DNA as a ‘liquid biopsy’ to supplement non-invasive biopsies for genetic and epigenetic characterization and monitoring of solid cancers. One of the epigenetic biomarkers that has gained more attention in CRC is aberrant DNA methylation of Septin 9 gene. In this study we try to evaluate the methylation of Septin 9 gene status in the cfDNA of the plasma in colorectal cancer patients. Plasma cell-free DNA samples were extracted from 30 patients with background of tumors or polyps and 30 samples from healthy individuals. Septin 9 methylation analysis was performed by using the bisulfite specific high resolution melting analysis. The result showed a sensitivity and specificity of 10% and 53.33%, respectively. In conclusion, our results demonstrated that Septin 9 DNA methylation in plasma determined by THP and BSP-HRM had not have sufficient accuracy." @default.
- W2904926213 created "2018-12-22" @default.
- W2904926213 creator A5014291630 @default.
- W2904926213 creator A5041216017 @default.
- W2904926213 creator A5063914461 @default.
- W2904926213 creator A5077536219 @default.
- W2904926213 date "2018-01-01" @default.
- W2904926213 modified "2023-10-16" @default.
- W2904926213 title "Aberrant SEPT9 methylation in plasma cell-free DNA of CRC patients" @default.
- W2904926213 doi "https://doi.org/10.4066/biomedicalresearch.29-18-951" @default.
- W2904926213 hasPublicationYear "2018" @default.
- W2904926213 type Work @default.
- W2904926213 sameAs 2904926213 @default.
- W2904926213 citedByCount "1" @default.
- W2904926213 countsByYear W29049262132021 @default.
- W2904926213 crossrefType "journal-article" @default.
- W2904926213 hasAuthorship W2904926213A5014291630 @default.
- W2904926213 hasAuthorship W2904926213A5041216017 @default.
- W2904926213 hasAuthorship W2904926213A5063914461 @default.
- W2904926213 hasAuthorship W2904926213A5077536219 @default.
- W2904926213 hasBestOaLocation W29049262131 @default.
- W2904926213 hasConcept C104317684 @default.
- W2904926213 hasConcept C121608353 @default.
- W2904926213 hasConcept C142724271 @default.
- W2904926213 hasConcept C1491633281 @default.
- W2904926213 hasConcept C150194340 @default.
- W2904926213 hasConcept C152110520 @default.
- W2904926213 hasConcept C172680121 @default.
- W2904926213 hasConcept C179411191 @default.
- W2904926213 hasConcept C189235521 @default.
- W2904926213 hasConcept C190727270 @default.
- W2904926213 hasConcept C2775934546 @default.
- W2904926213 hasConcept C2775959680 @default.
- W2904926213 hasConcept C2778258057 @default.
- W2904926213 hasConcept C2779234561 @default.
- W2904926213 hasConcept C2779529041 @default.
- W2904926213 hasConcept C33288867 @default.
- W2904926213 hasConcept C41091548 @default.
- W2904926213 hasConcept C45472230 @default.
- W2904926213 hasConcept C502942594 @default.
- W2904926213 hasConcept C526805850 @default.
- W2904926213 hasConcept C54355233 @default.
- W2904926213 hasConcept C71924100 @default.
- W2904926213 hasConcept C85813293 @default.
- W2904926213 hasConcept C86803240 @default.
- W2904926213 hasConceptScore W2904926213C104317684 @default.
- W2904926213 hasConceptScore W2904926213C121608353 @default.
- W2904926213 hasConceptScore W2904926213C142724271 @default.
- W2904926213 hasConceptScore W2904926213C1491633281 @default.
- W2904926213 hasConceptScore W2904926213C150194340 @default.
- W2904926213 hasConceptScore W2904926213C152110520 @default.
- W2904926213 hasConceptScore W2904926213C172680121 @default.
- W2904926213 hasConceptScore W2904926213C179411191 @default.
- W2904926213 hasConceptScore W2904926213C189235521 @default.
- W2904926213 hasConceptScore W2904926213C190727270 @default.
- W2904926213 hasConceptScore W2904926213C2775934546 @default.
- W2904926213 hasConceptScore W2904926213C2775959680 @default.
- W2904926213 hasConceptScore W2904926213C2778258057 @default.
- W2904926213 hasConceptScore W2904926213C2779234561 @default.
- W2904926213 hasConceptScore W2904926213C2779529041 @default.
- W2904926213 hasConceptScore W2904926213C33288867 @default.
- W2904926213 hasConceptScore W2904926213C41091548 @default.
- W2904926213 hasConceptScore W2904926213C45472230 @default.
- W2904926213 hasConceptScore W2904926213C502942594 @default.
- W2904926213 hasConceptScore W2904926213C526805850 @default.
- W2904926213 hasConceptScore W2904926213C54355233 @default.
- W2904926213 hasConceptScore W2904926213C71924100 @default.
- W2904926213 hasConceptScore W2904926213C85813293 @default.
- W2904926213 hasConceptScore W2904926213C86803240 @default.
- W2904926213 hasIssue "20" @default.
- W2904926213 hasLocation W29049262131 @default.
- W2904926213 hasOpenAccess W2904926213 @default.
- W2904926213 hasPrimaryLocation W29049262131 @default.
- W2904926213 hasRelatedWork W2609822003 @default.
- W2904926213 hasRelatedWork W2783456955 @default.
- W2904926213 hasRelatedWork W2904926213 @default.
- W2904926213 hasRelatedWork W2983668961 @default.
- W2904926213 hasRelatedWork W3004424038 @default.
- W2904926213 hasRelatedWork W3126924194 @default.
- W2904926213 hasRelatedWork W3161067307 @default.
- W2904926213 hasRelatedWork W3206050708 @default.
- W2904926213 hasRelatedWork W4223444440 @default.
- W2904926213 hasRelatedWork W4316469637 @default.
- W2904926213 hasVolume "29" @default.
- W2904926213 isParatext "false" @default.
- W2904926213 isRetracted "false" @default.
- W2904926213 magId "2904926213" @default.
- W2904926213 workType "article" @default.