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• W2904990403 abstract "Abstract BACKGROUND Although many studies have reported that the presence of minor or major ST-T change of electrocardiography (ECG) was associated with a risk of cardiovascular events, it is not clear whether there is a difference in the prognostic power depending on the summation of ST-T area (ST-Tarea) assessed by a quantitative method. METHODS Electrocardiograms were performed in 834 clinical patients with one or more cardiovascular risks. ST-Tarea was assessed as the area enclosed by the baseline from the end of the QRS complex to the end of the ST-T segment using a computerized quantitative method. We used the lower magnitude of ST-Tarea in the V5 or V6 lead for the analysis. RESULTS After a mean follow-up 8.4 ± 2.9 years (7,001 person-years), there were 92 cardiovascular events. With adjustment for covariates, the results from Cox proportional hazards models (Model 1) suggested that the lowest quartile of ST-Tarea was associated with a higher risk for cardiovascular outcome compared with the remaining quartile groups (hazard ratio, 2.08; 95% confidence interval, 1.36–3.16, P &lt; 0.01). Even when adding the ECG left ventricular hypertrophy by Cornell voltage (Model 2) and Cornell product (Model 3) to Model 1, the significance remained (both P &lt; 0.01). When we used ST-Tarea as a continuous variable substitute for the lowest quartile of ST-Tarea, these associations were similar in all models (all P &lt; 0.01). CONCLUSION The lower summations of ST-T area assessed by a computerized quantitative method were associated with increased risk of cardiovascular disease incidence in a clinical population." @default.
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• W2904990403 date "2018-12-08" @default.
• W2904990403 modified "2023-09-27" @default.
• W2904990403 title "Electrocardiographic ST-T Area Assessed by a Computerized Quantitative Method and Its Relation to Cardiovascular Events: The J-HOP Study" @default.
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• W2904990403 doi "https://doi.org/10.1093/ajh/hpy180" @default.
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