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- W2904990515 abstract "Niosomes (the nonionic surfactant vesicles), considered as novel drug delivery systems, can improve the solubility and stability of natural pharmaceutical molecules. They are established to provide targeting and controlled release of natural pharmaceutical compounds. Many factors can influence on niosome construction such as the preparation method, type and amount of surfactant, drug entrapment, temperature of lipids hydration, and the packing factor. The present review discusses about the most important features of niosomes such as their diverse structures, the different preparation approaches, characterization techniques, factors that affect their stability, their use by various routes of administration, their therapeutic applications in comparison with natural drugs, and specially the brain targeting with niosomes-ligand conjugation. It also provides recent data about the various types of ligand agents which make available active targeting drug delivery to the central neuron system. This system has an optimistic upcoming in pharmaceutical uses, mostly with the improving availability of innovative schemes to overcome blood-brain barrier and targeting the niosomes to the brain." @default.
- W2904990515 created "2018-12-22" @default.
- W2904990515 creator A5005364939 @default.
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- W2904990515 creator A5041421535 @default.
- W2904990515 creator A5052618241 @default.
- W2904990515 creator A5064617965 @default.
- W2904990515 date "2018-12-11" @default.
- W2904990515 modified "2023-10-10" @default.
- W2904990515 title "Niosome: A Promising Nanocarrier for Natural Drug Delivery through Blood-Brain Barrier" @default.
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- W2904990515 doi "https://doi.org/10.1155/2018/6847971" @default.
- W2904990515 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6311792" @default.
- W2904990515 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30651728" @default.
- W2904990515 hasPublicationYear "2018" @default.
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