Matches in SemOpenAlex for { <https://semopenalex.org/work/W2905086722> ?p ?o ?g. }
- W2905086722 abstract "Neisseria meningitidis colonizes at a nasopharynx of human as a unique host and has many strains that are auxotrophs for amino acids for their growth. To cause invasive meningococcal diseases (IMD) such as sepsis and meningitis, N. meningitidis passes through epithelial and endothelial barriers and infiltrates into blood and cerebrospinal fluid as well as epithelial and endothelial cells. However, meningococcal nutrients, including cysteine, become less abundant when it more deeply infiltrates the human body even during inflammation, such that N. meningitidis has to acquire nutrients in order to survive/persist, disseminate, and proliferate in humans. This was the first study to examine the relationship between meningococcal cysteine acquisition and the pathogenesis of meningococcal infections. The results of the present study provide insights into the mechanisms by which pathogens with auxotrophs acquire nutrients in hosts and may also contribute to the development of treatments and prevention strategies for IMD." @default.
- W2905086722 created "2018-12-22" @default.
- W2905086722 creator A5010867165 @default.
- W2905086722 creator A5016165244 @default.
- W2905086722 creator A5027781657 @default.
- W2905086722 creator A5027795108 @default.
- W2905086722 creator A5048322506 @default.
- W2905086722 date "2018-12-21" @default.
- W2905086722 modified "2023-09-24" @default.
- W2905086722 title "The Meningococcal Cysteine Transport System Plays a Crucial Role in <i>Neisseria meningitidis</i> Survival in Human Brain Microvascular Endothelial Cells" @default.
- W2905086722 cites W124779894 @default.
- W2905086722 cites W1532933231 @default.
- W2905086722 cites W1552890707 @default.
- W2905086722 cites W1558162435 @default.
- W2905086722 cites W1563378958 @default.
- W2905086722 cites W1587983189 @default.
- W2905086722 cites W1660023118 @default.
- W2905086722 cites W1662846517 @default.
- W2905086722 cites W1900670425 @default.
- W2905086722 cites W1902587054 @default.
- W2905086722 cites W1969066316 @default.
- W2905086722 cites W1972661416 @default.
- W2905086722 cites W1972823357 @default.
- W2905086722 cites W1974844310 @default.
- W2905086722 cites W1979768873 @default.
- W2905086722 cites W1981625038 @default.
- W2905086722 cites W1984153512 @default.
- W2905086722 cites W1989444563 @default.
- W2905086722 cites W1998371917 @default.
- W2905086722 cites W1999701076 @default.
- W2905086722 cites W2000056524 @default.
- W2905086722 cites W2003991742 @default.
- W2905086722 cites W2007715550 @default.
- W2905086722 cites W2007754595 @default.
- W2905086722 cites W2013292129 @default.
- W2905086722 cites W2013932696 @default.
- W2905086722 cites W2014982379 @default.
- W2905086722 cites W2016686226 @default.
- W2905086722 cites W2018045909 @default.
- W2905086722 cites W2027733516 @default.
- W2905086722 cites W2036733905 @default.
- W2905086722 cites W2038374897 @default.
- W2905086722 cites W2040779438 @default.
- W2905086722 cites W2041675917 @default.
- W2905086722 cites W2043884503 @default.
- W2905086722 cites W2048424287 @default.
- W2905086722 cites W2054112570 @default.
- W2905086722 cites W2057611573 @default.
- W2905086722 cites W2060932374 @default.
- W2905086722 cites W2068004788 @default.
- W2905086722 cites W2083463655 @default.
- W2905086722 cites W2085285106 @default.
- W2905086722 cites W2085566004 @default.
- W2905086722 cites W2087349850 @default.
- W2905086722 cites W2097691801 @default.
- W2905086722 cites W2098229789 @default.
- W2905086722 cites W2099839877 @default.
- W2905086722 cites W2099968943 @default.
- W2905086722 cites W2100121921 @default.
- W2905086722 cites W2100412795 @default.
- W2905086722 cites W2102186420 @default.
- W2905086722 cites W2102730007 @default.
- W2905086722 cites W2105188944 @default.
- W2905086722 cites W2109363146 @default.
- W2905086722 cites W2128022438 @default.
- W2905086722 cites W2128879290 @default.
- W2905086722 cites W2133177486 @default.
- W2905086722 cites W2137012093 @default.
- W2905086722 cites W2137108187 @default.
- W2905086722 cites W2138332261 @default.
- W2905086722 cites W2142200288 @default.
- W2905086722 cites W2148435514 @default.
- W2905086722 cites W2149435282 @default.
- W2905086722 cites W2149474172 @default.
- W2905086722 cites W2149907341 @default.
- W2905086722 cites W2151152170 @default.
- W2905086722 cites W2154491135 @default.
- W2905086722 cites W2157370926 @default.
- W2905086722 cites W2157845870 @default.
- W2905086722 cites W2160423401 @default.
- W2905086722 cites W2160696665 @default.
- W2905086722 cites W2163952229 @default.
- W2905086722 cites W2172226727 @default.
- W2905086722 cites W2221703937 @default.
- W2905086722 cites W2269583392 @default.
- W2905086722 cites W2273707745 @default.
- W2905086722 cites W2277511284 @default.
- W2905086722 cites W2501759063 @default.
- W2905086722 cites W2557696921 @default.
- W2905086722 cites W2576942929 @default.
- W2905086722 cites W2592277669 @default.
- W2905086722 cites W2605275799 @default.
- W2905086722 cites W2613230166 @default.
- W2905086722 cites W2761860903 @default.
- W2905086722 cites W2768012212 @default.
- W2905086722 cites W2790107617 @default.
- W2905086722 cites W4211242412 @default.
- W2905086722 cites W4232031254 @default.
- W2905086722 doi "https://doi.org/10.1128/mbio.02332-18" @default.
- W2905086722 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6299482" @default.