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- W2905087206 abstract "Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease marked by dry mouth/dry eye symptoms as a result of the destruction of the salivary and lacrimal glands. Patients with pSS may be at risk for the development of mucosa-associated lymphoid tissue (MALT) lymphoma. Testing of autoantibodies in the oral fluid of patients with pSS or MALT lymphoma using immunoassays may lead to a simple and noninvasive clinical tool for diagnostic or prognostic applications. In this chapter, we describe the procedures and protocols for determining autoantibodies to salivary gland antigens with proteomics-related methods, including 2D gel electrophoresis, liquid chromatography-tandem mass spectrometry (LC-MS/MS), Western blotting, protein microarray, and enzyme-linked immunosorbent assay (ELISA)." @default.
- W2905087206 created "2018-12-22" @default.
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- W2905087206 date "2018-12-12" @default.
- W2905087206 modified "2023-09-26" @default.
- W2905087206 title "Determination of Autoantibodies to Salivary Gland Antigens" @default.
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- W2905087206 doi "https://doi.org/10.1007/978-1-4939-8949-2_9" @default.
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