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- W2905534163 abstract "To evaluate early treatment outcomes of half-time photodynamic therapy (PDT) in patients with central serous chorioretinopathy (CSC).The anatomical and functional results were assessed for 24 eyes of 23 patients with CSC treated with half-time PDT in this prospective case series. Central foveal thickness (CFT) and subfoveal choroidal thickness (SCT) were evaluated by spectral-domain optical coherence tomography (SD-OCT), and mean retinal sensitivities and fixation characteristics were evaluated by MP-1 microperimetry at baseline and 1 day, 3 days, 1 week, 1 month, and 3 months after treatment.Observations 1 day after treatment revealed an increase in both SCT and CFT and a decrease in retinal sensitivity (P = .013; P = .02; and P = .02, respectively). The CFT significantly resolved 1 month after treatment (P = .002), and the SCT significantly resolved 7 days after treatment (P = .011). Although an immediate decrease in retinal sensitivity was observed at post-treatment day 1 (P = .02), the greatest reduction in retinal sensitivity was observed 3 days after treatment(P = .009), and then a tendency to increase was seen at subsequent visits.Despite early anatomical and functional impairments, such as an increase in CFT and SCT and a decrease in retinal sensitivity immediately after half-time PDT, best-corrected visual acuity and retinal sensitivity improved significantly 3 months after treatment. Half-time PDT is associated with early transient deterioration, but not with permanent adverse effect in patients with CSC. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:932-940.]." @default.
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- W2905534163 date "2018-12-01" @default.
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- W2905534163 title "Morphological and Functional Changes Immediately After Half-Time Photodynamic Therapy in Patients With Central Serous Chorioretinopathy" @default.
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- W2905534163 doi "https://doi.org/10.3928/23258160-20181203-05" @default.
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