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• W2905610961 abstract "Analysis of an antimicrobial culture broth extract of the sponge-derived actinomycete Streptomyces sp. (strain G246) led to the isolation of two new lavandulylated flavonoids, 6-lavandulyl-7-methoxy-5,2′,4′-trihydroxylflavanone (1) and 5′-lavandulyl-4′-methoxy-2,4,2′,6′-tetrahydroxylchalcone (2), along with eight known compounds 3–10. Their structures were established by spectral data analysis, including MS, 1D, 2D-NMR and CD. The absolute configurations of 1 and 2 were suggested by comparison of their experimental and calculated electronic circular dichroism spectra. All the isolated compounds were evaluated for their antimicrobial activity against a panel of clinically significant microorganisms. Compounds 1 and 2 had a broad-spectrum of antimicrobial activity. Additionally, except the strain Escherichia coli, compound 2 exhibited remarkable inhibitory activity against Pseudomonas aeruginosa, Salmonella enterica, Enterococcus faecalis, Staphylococcus aureus, Bacillus cereus, and Candida albicans strains." @default.
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• W2905610961 date "2018-12-23" @default.
• W2905610961 modified "2023-09-27" @default.
• W2905610961 title "Antimicrobial lavandulylated flavonoids from a sponge-derived actinomycete" @default.
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• W2905610961 doi "https://doi.org/10.1080/14786419.2018.1538219" @default.
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