FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2905810069> ?p ?o ?g. }

• W2905810069 abstract "Abstract Bacterial cell division is a fundamental process that results in the physical separation of a mother cell into two daughter cells and involves a set of proteins known as the divisome. Among them, the FtsQ/FtsB/FtsL complex was known as a scaffold protein complex, but its overall structure and exact function is not precisely known. In this study, we have determined the crystal structure of the periplasmic domain of FtsQ in complex with the C-terminal fragment of FtsB, and showed that the C-terminal region of FtsB is a key binding region of FtsQ via mutational analysis in vitro and in vivo . We also obtained the solution structure of the periplasmic FtsQ/FtsB/FtsL complex by small angle X-ray scattering (SAXS), which reveals its structural organization. Interestingly, the SAXS and analytical gel filtration data showed that the FtsQ/FtsB/FtsL complex forms a 2:2:2 heterohexameric assembly in solution with the “Y” shape. Based on the model, the N-terminal directions of FtsQ and the FtsB/FtsL complex should be opposite, suggesting that the Y-shaped FtsQ/FtsB/FtsL complex might fit well into the curved membrane for membrane anchoring." @default.
• W2905810069 created "2019-01-01" @default.
• W2905810069 creator A5022813627 @default.
• W2905810069 creator A5032095282 @default.
• W2905810069 creator A5046266336 @default.
• W2905810069 creator A5055862551 @default.
• W2905810069 creator A5060992488 @default.
• W2905810069 creator A5083251665 @default.
• W2905810069 date "2018-12-24" @default.
• W2905810069 modified "2023-10-17" @default.
• W2905810069 title "Structural Insights into the FtsQ/FtsB/FtsL Complex, a Key Component of the Divisome" @default.
• W2905810069 cites W1513966234 @default.
• W2905810069 cites W1539796472 @default.
• W2905810069 cites W1568160267 @default.
• W2905810069 cites W1829689588 @default.
• W2905810069 cites W1934579812 @default.
• W2905810069 cites W1959649751 @default.
• W2905810069 cites W1967131751 @default.
• W2905810069 cites W1975313581 @default.
• W2905810069 cites W1980906691 @default.
• W2905810069 cites W1985169370 @default.
• W2905810069 cites W1992191979 @default.
• W2905810069 cites W1994286350 @default.
• W2905810069 cites W2000339963 @default.
• W2905810069 cites W2013881981 @default.
• W2905810069 cites W2013931680 @default.
• W2905810069 cites W2026580217 @default.
• W2905810069 cites W2028328535 @default.
• W2905810069 cites W2035503835 @default.
• W2905810069 cites W2038840577 @default.
• W2905810069 cites W2047670590 @default.
• W2905810069 cites W2050091361 @default.
• W2905810069 cites W2058858340 @default.
• W2905810069 cites W2066088601 @default.
• W2905810069 cites W2069087157 @default.
• W2905810069 cites W2104267936 @default.
• W2905810069 cites W2110299776 @default.
• W2905810069 cites W2110310254 @default.
• W2905810069 cites W2111198021 @default.
• W2905810069 cites W2124983865 @default.
• W2905810069 cites W2126211773 @default.
• W2905810069 cites W2128428835 @default.
• W2905810069 cites W2135807487 @default.
• W2905810069 cites W2145466667 @default.
• W2905810069 cites W2149200290 @default.
• W2905810069 cites W2149856185 @default.
• W2905810069 cites W2149885731 @default.
• W2905810069 cites W2150010294 @default.
• W2905810069 cites W2153307913 @default.
• W2905810069 cites W2158336252 @default.
• W2905810069 cites W2166676244 @default.
• W2905810069 cites W2168777174 @default.
• W2905810069 cites W2324515915 @default.
• W2905810069 cites W2342190509 @default.
• W2905810069 cites W2412551864 @default.
• W2905810069 cites W2463992938 @default.
• W2905810069 cites W2774438235 @default.
• W2905810069 cites W2795292973 @default.
• W2905810069 cites W2810823843 @default.
• W2905810069 doi "https://doi.org/10.1038/s41598-018-36001-2" @default.
• W2905810069 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6305486" @default.
• W2905810069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30584256" @default.
• W2905810069 hasPublicationYear "2018" @default.
• W2905810069 type Work @default.
• W2905810069 sameAs 2905810069 @default.
• W2905810069 citedByCount "27" @default.
• W2905810069 countsByYear W29058100692019 @default.
• W2905810069 countsByYear W29058100692020 @default.
• W2905810069 countsByYear W29058100692021 @default.
• W2905810069 countsByYear W29058100692022 @default.
• W2905810069 countsByYear W29058100692023 @default.
• W2905810069 crossrefType "journal-article" @default.
• W2905810069 hasAuthorship W2905810069A5022813627 @default.
• W2905810069 hasAuthorship W2905810069A5032095282 @default.
• W2905810069 hasAuthorship W2905810069A5046266336 @default.
• W2905810069 hasAuthorship W2905810069A5055862551 @default.
• W2905810069 hasAuthorship W2905810069A5060992488 @default.
• W2905810069 hasAuthorship W2905810069A5083251665 @default.
• W2905810069 hasBestOaLocation W29058100691 @default.
• W2905810069 hasConcept C104317684 @default.
• W2905810069 hasConcept C144647389 @default.
• W2905810069 hasConcept C1491633281 @default.
• W2905810069 hasConcept C185592680 @default.
• W2905810069 hasConcept C201663137 @default.
• W2905810069 hasConcept C41625074 @default.
• W2905810069 hasConcept C547475151 @default.
• W2905810069 hasConcept C55493867 @default.
• W2905810069 hasConcept C85813293 @default.
• W2905810069 hasConcept C86803240 @default.
• W2905810069 hasConcept C95444343 @default.
• W2905810069 hasConceptScore W2905810069C104317684 @default.
• W2905810069 hasConceptScore W2905810069C144647389 @default.
• W2905810069 hasConceptScore W2905810069C1491633281 @default.
• W2905810069 hasConceptScore W2905810069C185592680 @default.
• W2905810069 hasConceptScore W2905810069C201663137 @default.
• W2905810069 hasConceptScore W2905810069C41625074 @default.
• W2905810069 hasConceptScore W2905810069C547475151 @default.
• W2905810069 hasConceptScore W2905810069C55493867 @default.
• W2905810069 hasConceptScore W2905810069C85813293 @default.
• W2905810069 hasConceptScore W2905810069C86803240 @default.

• next