FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2905911348> ?p ?o ?g. }

• W2905911348 endingPage "221" @default.
• W2905911348 startingPage "181" @default.
• W2905911348 abstract "Dioxygenases belong to one of the three major classes of heme-based enzymes that utilize atmospheric O2 as a substrate. Oxidases, such as cytochrome c oxidase, reduce O2 to two water molecules by utilizing four electrons and four protons, and harness the redox energy to pump four protons across the protein matrix. Monooxygenases, such as P450, convert one atom of dioxygen to a water by consuming two electrons and two protons, and exploit the redox energy to insert the other oxygen atom into an organic substrate. Dioxygenases, including tryptophan dioxygenase (TDO) and indoleamine 2,3-dioxygenase 1 (IDO1), are unique, and least understood, as they are capable of inserting both atoms of O2 into Trp without using any electrons and protons. In Part A of this chapter, we review the structure and function relationships of human TDO and IDO1 and compare them with those of bacterial TDOs and two dioxygenase analogs, PrnB and MarE. In Part B we outline the mechanisms by which the TDO and IDO1 functions are regulated in vivo by a variety of effectors under various (patho)physiological conditions." @default.
• W2905911348 created "2019-01-01" @default.
• W2905911348 creator A5007095541 @default.
• W2905911348 creator A5012454276 @default.
• W2905911348 creator A5051826956 @default.
• W2905911348 creator A5059629802 @default.
• W2905911348 creator A5079934230 @default.
• W2905911348 date "2018-10-03" @default.
• W2905911348 modified "2023-09-27" @default.
• W2905911348 title "Structure, Function and Regulation of Human Heme-based Dioxygenases" @default.
• W2905911348 cites W110237296 @default.
• W2905911348 cites W1487436709 @default.
• W2905911348 cites W1526968566 @default.
• W2905911348 cites W1549303643 @default.
• W2905911348 cites W1558363775 @default.
• W2905911348 cites W1569947394 @default.
• W2905911348 cites W1580449107 @default.
• W2905911348 cites W1581678191 @default.
• W2905911348 cites W1582908944 @default.
• W2905911348 cites W1584719926 @default.
• W2905911348 cites W1591909631 @default.
• W2905911348 cites W1597117184 @default.
• W2905911348 cites W1602589915 @default.
• W2905911348 cites W1646303100 @default.
• W2905911348 cites W1798211609 @default.
• W2905911348 cites W18268914 @default.
• W2905911348 cites W1834981029 @default.
• W2905911348 cites W1906899252 @default.
• W2905911348 cites W1963592955 @default.
• W2905911348 cites W1967372919 @default.
• W2905911348 cites W1967404929 @default.
• W2905911348 cites W1967706256 @default.
• W2905911348 cites W1971690451 @default.
• W2905911348 cites W1972550144 @default.
• W2905911348 cites W1973251492 @default.
• W2905911348 cites W1975033608 @default.
• W2905911348 cites W1975262546 @default.
• W2905911348 cites W1975345483 @default.
• W2905911348 cites W1978870153 @default.
• W2905911348 cites W1980040544 @default.
• W2905911348 cites W1984310018 @default.
• W2905911348 cites W1989044153 @default.
• W2905911348 cites W1989406212 @default.
• W2905911348 cites W1991344565 @default.
• W2905911348 cites W1992248511 @default.
• W2905911348 cites W1993166724 @default.
• W2905911348 cites W1996177596 @default.
• W2905911348 cites W1998142996 @default.
• W2905911348 cites W1999089069 @default.
• W2905911348 cites W2000254823 @default.
• W2905911348 cites W2003303867 @default.
• W2905911348 cites W2003877760 @default.
• W2905911348 cites W2005133530 @default.
• W2905911348 cites W2005383727 @default.
• W2905911348 cites W2007316487 @default.
• W2905911348 cites W2008343182 @default.
• W2905911348 cites W2008724539 @default.
• W2905911348 cites W2009930767 @default.
• W2905911348 cites W2010343273 @default.
• W2905911348 cites W2010946709 @default.
• W2905911348 cites W2011062975 @default.
• W2905911348 cites W2012836981 @default.
• W2905911348 cites W2015260577 @default.
• W2905911348 cites W2015933085 @default.
• W2905911348 cites W2017371906 @default.
• W2905911348 cites W2018058993 @default.
• W2905911348 cites W2020783130 @default.
• W2905911348 cites W2021388708 @default.
• W2905911348 cites W2026679562 @default.
• W2905911348 cites W2026987279 @default.
• W2905911348 cites W2028323326 @default.
• W2905911348 cites W2030213852 @default.
• W2905911348 cites W2031990985 @default.
• W2905911348 cites W2032490555 @default.
• W2905911348 cites W2036254916 @default.
• W2905911348 cites W2039596618 @default.
• W2905911348 cites W2039779725 @default.
• W2905911348 cites W2040636315 @default.
• W2905911348 cites W2043672573 @default.
• W2905911348 cites W2046425294 @default.
• W2905911348 cites W2053217888 @default.
• W2905911348 cites W2055414731 @default.
• W2905911348 cites W2060903877 @default.
• W2905911348 cites W2063033265 @default.
• W2905911348 cites W2064987952 @default.
• W2905911348 cites W2066076970 @default.
• W2905911348 cites W2066682189 @default.
• W2905911348 cites W2068122136 @default.
• W2905911348 cites W2068344738 @default.
• W2905911348 cites W2068469924 @default.
• W2905911348 cites W2071848867 @default.
• W2905911348 cites W2073221052 @default.
• W2905911348 cites W2073805658 @default.
• W2905911348 cites W2074495555 @default.
• W2905911348 cites W2074605568 @default.
• W2905911348 cites W2076555138 @default.
• W2905911348 cites W2078075518 @default.
• W2905911348 cites W2081623409 @default.

• next