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• W2905957965 abstract "The vascular endothelial growth factor (VEGF) system has been shown to play a crucial role in several neuropathological processes. Temporal lobe epilepsy (TLE) is the most common focal epilepsy type in adult humans. We assessed the protein expression levels of VEGF-A, VEGF-B, and VEGF-C, their specific receptors VEGFR-2 and -3, their accessory receptors neuropilins 1 and 2, and PI3 and Akt kinases, in temporal neocortex from pharmacoresistant TLE (PR-TLE) patients and control subjects by western blotting. All proteins were found to be significantly overexpressed in samples of PR-TLE patients, indicating that the VEGF system contributes to PR-TLE pathogenesis and should be further studied." @default.
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• W2905957965 date "2019-03-01" @default.
• W2905957965 modified "2023-10-10" @default.
• W2905957965 title "Increased protein expression of VEGF-A, VEGF-B, VEGF-C and their receptors in the temporal neocortex of pharmacoresistant temporal lobe epilepsy patients" @default.
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• W2905957965 doi "https://doi.org/10.1016/j.jneuroim.2018.12.007" @default.
• W2905957965 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30597392" @default.
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