FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2906062012> ?p ?o ?g. }

• W2906062012 endingPage "179" @default.
• W2906062012 startingPage "171" @default.
• W2906062012 abstract "Background Paradigm has shifted from 2D to image-guided adaptive brachytherapy (IGABT) for locally advanced cervix cancer (LACC). Increasing reports from pioneering institutions and large retrospective multicenter series have demonstrated improvements in outcome and reduction in toxicity with IGABT. However, there is scarcity of data on magnetic resonance (MR)-IGABT in Chinese patients. Purpose To evaluate the clinical outcome of MR-IGABT for LACC in a single institution in Hong Kong. Material and Methods Patients with FIGO stage IB-IVA LACC treated with definitive external beam radiotherapy +/− concurrent cisplatin followed by MR-IGABT from January 2015 to January 2018 were included. Brachytherapy planning and dose reporting followed the GEC-ESTRO recommendations. Dosimetric and clinical outcomes including local control (LC), pelvic control (PC), cancer-specific survival, overall survival (OS), and toxicity were analyzed. Results Forty-two consecutive patients were included. 71% were FIGO stage IIB or above; 52% had pelvic node involvement. Median high-risk clinical target volume (HRCTV) was 34.7 cm3 (12.3–155.1 cm3). Median dose to HRCTV D90 was 88.5 Gy (63.4–113.4 Gy) (EQD210). Median doses to the D2cc of bladder, rectum, sigmoid, and small bowel were 83.1 Gy, 67.5 Gy, 69.0 Gy, and 68.9 Gy (EQD23), respectively. Median followup was 20.3 months (4.0–35.1 months). 24-month actuarial LC, PC, cancer-specific survival, and OS were 90%, 84%, 90%, and 90%, respectively. Stratification by clinical variables showed that FIGO stage had significant impact on LC and dose to HRCTV on both LC and PC. Treatment was well tolerated without any severe late toxicity. Conclusions Intermediate-term results from systematic MR-IGABT for LACC demonstrate very promising outcomes with minimal toxicity. This fills the gap in evidence for MR-IGABT in Chinese patients." @default.
• W2906062012 created "2019-01-01" @default.
• W2906062012 creator A5018954981 @default.
• W2906062012 creator A5020690644 @default.
• W2906062012 creator A5026575639 @default.
• W2906062012 creator A5028532953 @default.
• W2906062012 creator A5044864465 @default.
• W2906062012 creator A5052526770 @default.
• W2906062012 creator A5053101301 @default.
• W2906062012 creator A5083958885 @default.
• W2906062012 creator A5090280050 @default.
• W2906062012 date "2019-03-01" @default.
• W2906062012 modified "2023-10-01" @default.
• W2906062012 title "MRI-guided adaptive brachytherapy for locally advanced cervix cancer: Treatment outcomes from a single institution in Hong Kong" @default.
• W2906062012 cites W1623479996 @default.
• W2906062012 cites W1966946680 @default.
• W2906062012 cites W1977479761 @default.
• W2906062012 cites W1978471035 @default.
• W2906062012 cites W1980444505 @default.
• W2906062012 cites W1984363009 @default.
• W2906062012 cites W1987269690 @default.
• W2906062012 cites W1994922565 @default.
• W2906062012 cites W1995699258 @default.
• W2906062012 cites W1999267929 @default.
• W2906062012 cites W2005626614 @default.
• W2906062012 cites W2014343721 @default.
• W2906062012 cites W2015588769 @default.
• W2906062012 cites W2020843880 @default.
• W2906062012 cites W2028679169 @default.
• W2906062012 cites W2029856598 @default.
• W2906062012 cites W2033905828 @default.
• W2906062012 cites W2034305918 @default.
• W2906062012 cites W2041683853 @default.
• W2906062012 cites W2042262831 @default.
• W2906062012 cites W2051404332 @default.
• W2906062012 cites W2058904677 @default.
• W2906062012 cites W2072836313 @default.
• W2906062012 cites W2076075334 @default.
• W2906062012 cites W2081977840 @default.
• W2906062012 cites W2083325737 @default.
• W2906062012 cites W2089120805 @default.
• W2906062012 cites W2091172221 @default.
• W2906062012 cites W2099245483 @default.
• W2906062012 cites W2122169072 @default.
• W2906062012 cites W2122321342 @default.
• W2906062012 cites W2128768289 @default.
• W2906062012 cites W2131860931 @default.
• W2906062012 cites W2152292894 @default.
• W2906062012 cites W2155153063 @default.
• W2906062012 cites W2172676478 @default.
• W2906062012 cites W2323840899 @default.
• W2906062012 cites W2341208453 @default.
• W2906062012 cites W2345268804 @default.
• W2906062012 cites W2399888821 @default.
• W2906062012 cites W2460848290 @default.
• W2906062012 cites W2517151534 @default.
• W2906062012 cites W2591916355 @default.
• W2906062012 cites W2675799240 @default.
• W2906062012 cites W2799773958 @default.
• W2906062012 cites W2917837889 @default.
• W2906062012 cites W4255462147 @default.
• W2906062012 doi "https://doi.org/10.1016/j.brachy.2018.11.007" @default.
• W2906062012 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30581053" @default.
• W2906062012 hasPublicationYear "2019" @default.
• W2906062012 type Work @default.
• W2906062012 sameAs 2906062012 @default.
• W2906062012 citedByCount "7" @default.
• W2906062012 countsByYear W29060620122020 @default.
• W2906062012 countsByYear W29060620122022 @default.
• W2906062012 countsByYear W29060620122023 @default.
• W2906062012 crossrefType "journal-article" @default.
• W2906062012 hasAuthorship W2906062012A5018954981 @default.
• W2906062012 hasAuthorship W2906062012A5020690644 @default.
• W2906062012 hasAuthorship W2906062012A5026575639 @default.
• W2906062012 hasAuthorship W2906062012A5028532953 @default.
• W2906062012 hasAuthorship W2906062012A5044864465 @default.
• W2906062012 hasAuthorship W2906062012A5052526770 @default.
• W2906062012 hasAuthorship W2906062012A5053101301 @default.
• W2906062012 hasAuthorship W2906062012A5083958885 @default.
• W2906062012 hasAuthorship W2906062012A5090280050 @default.
• W2906062012 hasConcept C121608353 @default.
• W2906062012 hasConcept C126322002 @default.
• W2906062012 hasConcept C126838900 @default.
• W2906062012 hasConcept C141071460 @default.
• W2906062012 hasConcept C146357865 @default.
• W2906062012 hasConcept C151730666 @default.
• W2906062012 hasConcept C2777416452 @default.
• W2906062012 hasConcept C2777740455 @default.
• W2906062012 hasConcept C2778220009 @default.
• W2906062012 hasConcept C2781074409 @default.
• W2906062012 hasConcept C2989005 @default.
• W2906062012 hasConcept C509974204 @default.
• W2906062012 hasConcept C71924100 @default.
• W2906062012 hasConcept C86803240 @default.
• W2906062012 hasConceptScore W2906062012C121608353 @default.
• W2906062012 hasConceptScore W2906062012C126322002 @default.
• W2906062012 hasConceptScore W2906062012C126838900 @default.
• W2906062012 hasConceptScore W2906062012C141071460 @default.

• next