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- W2906085706 abstract "A decision-making framework called NOMS (neurologic, oncologic, mechanical and systemic) facilitates and guides therapeutic decisions for patients with spinal metastases. Patients should be evaluated for signs of myelopathy or cauda equina syndrome. The Epidural Spinal Cord Compression (ESCC) scale facilitates reporting of the degree of radiographic spinal cord compression. A determination of the expected histology-specific tumor response to conventionally fractionated external beam radiation (cEBRT) and systemic therapy should be made. Radiation therapy effectively treats biologic pain for radiosensitive tumors such as multiple myeloma. Patients should undergo a careful evaluation of movement-associated pain as tumor-induced spinal instability is an independent indication for surgery. Determination of tumor-associated mechanical instability can be facilitated by the Spinal Instability Neoplastic Score (SINS). Herein, the authors present a case of spinal multiple myeloma managed using the NOMS framework and in consideration of current evidence and treatment paradigms." @default.
- W2906085706 created "2019-01-01" @default.
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- W2906085706 date "2018-11-01" @default.
- W2906085706 modified "2023-10-05" @default.
- W2906085706 title "Radiation-Sensitive Spine Tumor" @default.
- W2906085706 doi "https://doi.org/10.1093/med/9780190887773.003.0017" @default.
- W2906085706 hasPublicationYear "2018" @default.
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