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- W2906092431 abstract "Many women describe symptoms of memory loss or inattention during pregnancy and the early postpartum period (“pregnancy brain”). Data on the effect of pregnancy on cognitive function has been mixed. We sought to objectively evaluate executive function (EF) in the early pregnancy and postpartum period. Women with singleton gestations were recruited in the first trimester of pregnancy as part of a larger IRB approved prospective trial. EF performance was assessed in the first trimester and at 6 weeks postpartum using the Trail Making Test (TMT) of the Delis-Kaplan Executive Function System, the Stop Signal Task (SST), and the Delay Discounting Task (DDT). Perceived problems with EF were measured using the Behavior Rating Inventory of Executive Function – Adult self-report (BRIEF-A). Mental health was measured using the Euro Quality of Life (EQ-5D-3L) and Adult Self Report (ASR). Changes in EF were evaluated by paired student’s t-tests. 102 women completed EF assessment at both time points. Mean scores on the TMT and BRIEF were within average range. No self-reported differences in EF were observed between time points. Objective EF measures showed more impulsive behavior (p < 0.05), but improved cognitive flexibility (p < 0.0001) postpartum compared to the first trimester. Neither self-reported “overall health” nor the number of women reporting clinically significant levels of mental health-related symptoms differed between visits. Postpartum EF performance was worse than that in the first trimester, with the exception of cognitive flexibility, without subjective changes in health. These data suggest that cognitive function varies across pregnancy and that at least in the early postpartum period there are observable cognitive deficits. More study is needed to further longitudinally examine EF beyond 6 weeks postpartum." @default.
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- W2906092431 date "2019-01-01" @default.
- W2906092431 modified "2023-09-26" @default.
- W2906092431 title "1004: Longitudinal evaluation of executive function during pregnancy" @default.
- W2906092431 doi "https://doi.org/10.1016/j.ajog.2018.11.1028" @default.
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