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- W2906228210 abstract "Background: Airflow limitation is a mechanical pathophysiological condition occurring, either during physical exercise or at rest. Objective: Accurate measurement of airflow limitation in COPD patients and correlation between standard FEV1 (as an evidence for diagnosis and grading of airway obstruction) and Ventilatory Flow Limitation (VFL) as an accurate measurement of airflow limitation. Patients & Methods: Fourty patients with COPD from outpatient clinic and ten control persons were included. Tidal flow volume loop was drawn by plotting exercise tidal flow volume loop (ext FVL) inside maximal flow volume loop. End expiratory lung volume (EELV) and ventilatory flow limitation (VFL) was measured. They divided into 2 groups group I and group II Results: Regarding degree of VFL and EELV in both groups, Group II had significantly higher (P<0.000) VFL and EELV. All very severe COPD patients exhibited severe VFL. While only 27.3% of severe patients had severe VFL. The remaining 72.27% of severe COPD had moderate VFL. All mild and moderate COPD patients had mild VFL. Tables (1) showed degree of VFL among different groups. Normal persons did not present any VFL. Group II had significantly higher (P Conclusion: VFL and EELV are specific indices for airway obstruction in COPD patients and are correlated to the degree of severity." @default.
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- W2906228210 date "2018-09-15" @default.
- W2906228210 modified "2023-10-18" @default.
- W2906228210 title "Quantification of airflow limitation in chronic obstructive pulmonary disease" @default.
- W2906228210 doi "https://doi.org/10.1183/13993003.congress-2018.pa3401" @default.
- W2906228210 hasPublicationYear "2018" @default.
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